Co-infections, inflammation and oncogenesis: future directions for EBV research

AB Rickinson - Seminars in cancer biology, 2014 - Elsevier
Epstein–Barr virus (EBV) is aetiologically linked to a wide range of human tumours. Some
arise as accidents of the virus' lifestyle in its natural niche, the B lymphoid system; these …

[HTML][HTML] Helicobacter pylori: Commensal, symbiont or pathogen?

VI Reshetnyak, AI Burmistrov… - World journal of …, 2021 - ncbi.nlm.nih.gov
This review considers the data on Helicobacter pylori (H. pylori), which have been
accumulated over 40 years since its description as an etiological factor in gastrointestinal …

[PDF][PDF] Helicobacter pylori CagA elicits BRCAness to induce genome instability that may underlie bacterial gastric carcinogenesis

S Imai, T Ooki, N Murata-Kamiya, D Komura… - Cell Host & Microbe, 2021 - cell.com
Summary Infection with CagA-producing Helicobacter pylori plays a causative role in the
development of gastric cancer. Upon delivery into gastric epithelial cells, CagA deregulates …

A novel design of a multi-antigenic, multistage and multi-epitope vaccine against Helicobacter pylori: an in silico approach

B Meza, F Ascencio, AP Sierra-Beltrán, J Torres… - Infection, Genetics and …, 2017 - Elsevier
Helicobacter pylori have colonized the gastric mucosa of half of the population worldwide.
This bacterium is classified as a definitive type I carcinogen by the World Health …

TIFA Signaling in Gastric Epithelial Cells Initiates the cag Type 4 Secretion System-Dependent Innate Immune Response to Helicobacter pylori Infection

A Gall, RG Gaudet, SD Gray-Owen, NR Salama - MBio, 2017 - Am Soc Microbiol
Helicobacter pylori is a bacterial pathogen that colonizes the human stomach, causing
inflammation which, in some cases, leads to gastric ulcers and cancer. The clinical outcome …

How Helicobacter pylori senses, targets and interacts with the gastric epithelium

D Keilberg, KM Ottemann - Environmental microbiology, 2016 - Wiley Online Library
H elicobacter pylori is a human‐specific pathogen that chronically infects about 50% of the
world's population. After travelling through the harsh environment of the stomach lumen, H …

[HTML][HTML] Use of probiotics in the fight against Helicobacter pylori

P Ruggiero - World journal of gastrointestinal pathophysiology, 2014 - ncbi.nlm.nih.gov
After the discovery of Helicobacter pylori (H. pylori), and the evidence of its relationship with
gastric diseases, antibiotic-based therapies were developed, which efficacy was however …

Microbiota and the immune system—actors in the gastric cancer story

M Majewski, P Mertowska, S Mertowski, K Smolak… - Cancers, 2022 - mdpi.com
Simple Summary Stomach cancer is one of the most commonly diagnosed cancers in the
world. Although the number of new cases is decreasing year by year, the death rate for this …

Classification of Helicobacter pylori virulence factors: Is CagA a toxin or not?

J Knorr, V Ricci, M Hatakeyama, S Backert - Trends in microbiology, 2019 - cell.com
Since its discovery, Helicobacter pylori has been identified as the causative agent of various
gastric diseases. H. pylori produces myriads of disease-associated virulence factors. These …

Novel Insights of Lymphomagenesis of Helicobacter pylori-Dependent Gastric Mucosa-Associated Lymphoid Tissue Lymphoma

SH Kuo, MS Wu, KH Yeh, CW Lin, PN Hsu, LT Chen… - Cancers, 2019 - mdpi.com
Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is the most common subtype
of gastric lymphoma. Most gastric MALT lymphomas are characterized by their association …