The health effects of vitamin D supplementation: evidence from human studies

R Bouillon, D Manousaki, C Rosen… - Nature Reviews …, 2022 - nature.com
Vitamin D supplementation can prevent and cure nutritional rickets in infants and children.
Preclinical and observational data suggest that the vitamin D endocrine system has a wide …

Vitamin D's effect on immune function

PJ Martens, C Gysemans, A Verstuyf, C Mathieu - Nutrients, 2020 - mdpi.com
Ever since its discovery by Windhaus, the importance of the active metabolite of vitamin D (1,
25-dihydroxyvitamin D3; 1, 25-(OH) 2D3) has been ever expanding. In this review, the …

Clinical practice in the prevention, diagnosis and treatment of vitamin D deficiency: a central and eastern European expert consensus statement

P Pludowski, I Takacs, M Boyanov, Z Belaya… - Nutrients, 2022 - mdpi.com
Vitamin D deficiency has a high worldwide prevalence, but actions to improve this public
health problem are challenged by the heterogeneity of nutritional and clinical vitamin D …

Skeletal and extraskeletal actions of vitamin D: current evidence and outstanding questions

R Bouillon, C Marcocci, G Carmeliet, D Bikle… - Endocrine …, 2019 - academic.oup.com
The etiology of endemic rickets was discovered a century ago. Vitamin D is the precursor of
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …

Vitamin D and cardiovascular health

F de la Guía-Galipienso, M Martínez-Ferran… - Clinical Nutrition, 2021 - Elsevier
The principal source of vitamin D in humans is its biosynthesis in the skin through a
chemical reaction dependent on sun exposure. In lesser amounts, the vitamin can be …

[HTML][HTML] Low vitamin D status is associated with coronavirus disease 2019 outcomes: a systematic review and meta-analysis

N Liu, J Sun, X Wang, T Zhang, M Zhao, H Li - International Journal of …, 2021 - Elsevier
Background Observational studies suggest that the risk and clinical prognosis of coronavirus
disease 2019 (COVID-19) are related to low vitamin D status; however, the data are …

Consensus statement from 2nd International Conference on Controversies in Vitamin D

A Giustina, RA Adler, N Binkley, J Bollerslev… - Reviews in Endocrine …, 2020 - Springer
Abstract The 2 nd International Conference on Controversies in Vitamin D was held in
Monteriggioni (Siena), Italy, September 11-14, 2018. The aim of this meeting was to address …

An update on the effects of vitamin D on the immune system and autoimmune diseases

C Sîrbe, S Rednic, A Grama, TL Pop - International journal of molecular …, 2022 - mdpi.com
Vitamin D intervenes in calcium and phosphate metabolism and bone homeostasis.
Experimental studies have shown that 1, 25-dihydroxyvitamin D (calcitriol) generates …

Current vitamin D status in European and Middle East countries and strategies to prevent vitamin D deficiency: a position statement of the European Calcified Tissue …

P Lips, KD Cashman, C Lamberg-Allardt… - European journal of …, 2019 - academic.oup.com
Vitamin D deficiency (serum 25-hydroxyvitamin D (25 (OH) D)< 50 nmol/L or 20 ng/mL) is
common in Europe and the Middle East. It occurs in< 20% of the population in Northern …

[HTML][HTML] Global and regional prevalence of vitamin D deficiency in population-based studies from 2000 to 2022: A pooled analysis of 7.9 million participants

A Cui, T Zhang, P Xiao, Z Fan, H Wang… - Frontiers in Nutrition, 2023 - frontiersin.org
Background Vitamin D deficiency has been considered a global health issue in recent years.
However, there is still no study estimating the global and regional prevalence of vitamin D …