Advances of nanoparticles as drug delivery systems for disease diagnosis and treatment
Decades have passed since the first nanoparticles-base medicine was approved for human
cancer treatment, and the research and development of nanoparticles for drug delivery are …
cancer treatment, and the research and development of nanoparticles for drug delivery are …
[HTML][HTML] Emerging new therapeutic antibody derivatives for cancer treatment
S Jin, Y Sun, X Liang, X Gu, J Ning, Y Xu… - Signal transduction and …, 2022 - nature.com
Monoclonal antibodies constitute a promising class of targeted anticancer agents that
enhance natural immune system functions to suppress cancer cell activity and eliminate …
enhance natural immune system functions to suppress cancer cell activity and eliminate …
Biomimetic nanoerythrosome‐coated aptamer–DNA tetrahedron/maytansine conjugates: pH‐responsive and targeted cytotoxicity for HER2‐positive breast cancer
W Ma, Y Yang, J Zhu, W Jia, T Zhang, Z Liu… - Advanced …, 2022 - Wiley Online Library
DNA materials have emerged as potential nanocarriers for targeted cancer therapy to
precisely deliver cargos with specific purposes. The short half‐life and low bioavailability of …
precisely deliver cargos with specific purposes. The short half‐life and low bioavailability of …
Advances in antibody-based therapy in oncology
S Zinn, R Vazquez-Lombardi, C Zimmermann, P Sapra… - Nature cancer, 2023 - nature.com
Monoclonal antibodies are a growing class of targeted cancer therapeutics, characterized by
exquisite specificity, long serum half-life, high affinity and immune effector functions. In this …
exquisite specificity, long serum half-life, high affinity and immune effector functions. In this …
Tumor-targeted delivery of a STING agonist improves cancer immunotherapy
Y Wu, Y Fang, Q Wei, H Shi, H Tan… - Proceedings of the …, 2022 - National Acad Sciences
The cGAS-STING pathway is essential for immune defense against microbial pathogens and
malignant cells; as such, STING is an attractive target for cancer immunotherapy. However …
malignant cells; as such, STING is an attractive target for cancer immunotherapy. However …
[HTML][HTML] Monoclonal antibodies in cancer therapy
D Zahavi, L Weiner - Antibodies, 2020 - mdpi.com
Monoclonal antibody-based immunotherapy is now considered to be a main component of
cancer therapy, alongside surgery, radiation, and chemotherapy. Monoclonal antibodies …
cancer therapy, alongside surgery, radiation, and chemotherapy. Monoclonal antibodies …
A bioorthogonal system reveals antitumour immune function of pyroptosis
Bioorthogonal chemistry capable of operating in live animals is needed to investigate
biological processes such as cell death and immunity. Recent studies have identified a …
biological processes such as cell death and immunity. Recent studies have identified a …
[HTML][HTML] Recent advances in systemic therapy for hepatocellular carcinoma
H Zhang, W Zhang, L Jiang, Y Chen - Biomarker Research, 2022 - Springer
Hepatocellular carcinoma (HCC) is one of the most common and lethal malignant tumors in
the world. Therapeutic options for advanced HCC are limited. Systemic treatment, especially …
the world. Therapeutic options for advanced HCC are limited. Systemic treatment, especially …
[HTML][HTML] Antibody–drug conjugates for cancer therapy
Antibody–drug conjugates (ADCs) are novel drugs that exploit the specificity of a
monoclonal antibody (mAb) to reach target antigens expressed on cancer cells for the …
monoclonal antibody (mAb) to reach target antigens expressed on cancer cells for the …
[HTML][HTML] Cancer nanotechnology: current status and perspectives
JA Kemp, YJ Kwon - Nano convergence, 2021 - Springer
Modern medicine has been waging a war on cancer for nearly a century with no tangible
end in sight. Cancer treatments have significantly progressed, but the need to increase …
end in sight. Cancer treatments have significantly progressed, but the need to increase …