Advances of nanoparticles as drug delivery systems for disease diagnosis and treatment

R Liu, C Luo, Z Pang, J Zhang, S Ruan, M Wu… - Chinese chemical …, 2023 - Elsevier
Decades have passed since the first nanoparticles-base medicine was approved for human
cancer treatment, and the research and development of nanoparticles for drug delivery are …

[HTML][HTML] Emerging new therapeutic antibody derivatives for cancer treatment

S Jin, Y Sun, X Liang, X Gu, J Ning, Y Xu… - Signal transduction and …, 2022 - nature.com
Monoclonal antibodies constitute a promising class of targeted anticancer agents that
enhance natural immune system functions to suppress cancer cell activity and eliminate …

Biomimetic nanoerythrosome‐coated aptamer–DNA tetrahedron/maytansine conjugates: pH‐responsive and targeted cytotoxicity for HER2‐positive breast cancer

W Ma, Y Yang, J Zhu, W Jia, T Zhang, Z Liu… - Advanced …, 2022 - Wiley Online Library
DNA materials have emerged as potential nanocarriers for targeted cancer therapy to
precisely deliver cargos with specific purposes. The short half‐life and low bioavailability of …

Advances in antibody-based therapy in oncology

S Zinn, R Vazquez-Lombardi, C Zimmermann, P Sapra… - Nature cancer, 2023 - nature.com
Monoclonal antibodies are a growing class of targeted cancer therapeutics, characterized by
exquisite specificity, long serum half-life, high affinity and immune effector functions. In this …

Tumor-targeted delivery of a STING agonist improves cancer immunotherapy

Y Wu, Y Fang, Q Wei, H Shi, H Tan… - Proceedings of the …, 2022 - National Acad Sciences
The cGAS-STING pathway is essential for immune defense against microbial pathogens and
malignant cells; as such, STING is an attractive target for cancer immunotherapy. However …

[HTML][HTML] Monoclonal antibodies in cancer therapy

D Zahavi, L Weiner - Antibodies, 2020 - mdpi.com
Monoclonal antibody-based immunotherapy is now considered to be a main component of
cancer therapy, alongside surgery, radiation, and chemotherapy. Monoclonal antibodies …

A bioorthogonal system reveals antitumour immune function of pyroptosis

Q Wang, Y Wang, J Ding, C Wang, X Zhou, W Gao… - Nature, 2020 - nature.com
Bioorthogonal chemistry capable of operating in live animals is needed to investigate
biological processes such as cell death and immunity. Recent studies have identified a …

[HTML][HTML] Recent advances in systemic therapy for hepatocellular carcinoma

H Zhang, W Zhang, L Jiang, Y Chen - Biomarker Research, 2022 - Springer
Hepatocellular carcinoma (HCC) is one of the most common and lethal malignant tumors in
the world. Therapeutic options for advanced HCC are limited. Systemic treatment, especially …

[HTML][HTML] Antibody–drug conjugates for cancer therapy

U Hafeez, S Parakh, HK Gan, AM Scott - Molecules, 2020 - mdpi.com
Antibody–drug conjugates (ADCs) are novel drugs that exploit the specificity of a
monoclonal antibody (mAb) to reach target antigens expressed on cancer cells for the …

[HTML][HTML] Cancer nanotechnology: current status and perspectives

JA Kemp, YJ Kwon - Nano convergence, 2021 - Springer
Modern medicine has been waging a war on cancer for nearly a century with no tangible
end in sight. Cancer treatments have significantly progressed, but the need to increase …