Constitutive modeling is the cornerstone of computational and structural mechanics. In a
finite element analysis, the constitutive model is encoded in the material subroutine, a …

Constitutive modeling is a cornerstone for stress analysis of mechanical behaviors of
biological soft tissues. Recently, it has been shown that machine learning (ML) techniques …

This review article is concerned with the mathematical modelling of the mechanical
properties of the soft biological tissues that constitute the walls of arteries. Many important …

New experimental results on collagen fibre dispersion in human arterial layers have shown
that the dispersion in the tangential plane is more significant than that out of plane. A …

With heart and cardiovascular diseases continually challenging healthcare systems
worldwide, translating basic research on cardiac (patho) physiology into clinical care is …

Aortic disease is a significant cause of death in developed countries. The most common
forms of aortic disease are aneurysm, dissection, atherosclerotic occlusion and ageing …

Aortic dissections and aortic aneurysms are fatal events characterized by structural changes
to the aortic wall. The maximum diameter criterion, typically used for aneurysm rupture risk …

The established method of polarized microscopy in combination with a universal stage is
used to determine the layer-specific distributed collagen fibre orientations in 11 human non …

White matter in the brain is structurally anisotropic, consisting largely of bundles of aligned,
myelin-sheathed axonal fibers. White matter is believed to be mechanically anisotropic as …

Conduit arteries become stiffer with age due to alterations in their morphology and the
composition of the their major structural proteins, elastin and collagen. The elastic lamellae …