Data-driven tissue mechanics with polyconvex neural ordinary differential equations

V Tac, FS Costabal, AB Tepole - Computer Methods in Applied Mechanics …, 2022 - Elsevier
Data-driven methods are becoming an essential part of computational mechanics due to
their advantages over traditional material modeling. Deep neural networks are able to learn …

Benchmarking physics-informed frameworks for data-driven hyperelasticity

V Taç, K Linka, F Sahli-Costabal, E Kuhl… - Computational …, 2024 - Springer
Data-driven methods have changed the way we understand and model materials. However,
while providing unmatched flexibility, these methods have limitations such as reduced …

[HTML][HTML] Recent developments in vascular adventitial pathobiology: the dynamic adventitia as a complex regulator of vascular disease

MG Tinajero, AI Gotlieb - The American journal of pathology, 2020 - Elsevier
The adventitia, the outer layer of the blood vessel wall, may be the most complex layer of the
wall and may be the master regulator of wall physiology and pathobiology. This review …

On the benefits and pitfalls of analogies for innovative design: Ideation performance based on analogical distance, commonness, and modality of examples

J Chan, K Fu, C Schunn, J Cagan, K Wood… - 2011 - asmedigitalcollection.asme.org
Drawing inspiration from examples by analogy can be a powerful tool for innovative design
during conceptual ideation but also carries the risk of negative design outcomes (eg, design …

On fibre dispersion modelling of soft biological tissues: a review

GA Holzapfel, RW Ogden… - Proceedings of the …, 2019 - royalsocietypublishing.org
Collagen fibres within fibrous soft biological tissues such as artery walls, cartilage,
myocardiums, corneas and heart valves are responsible for their anisotropic mechanical …

Scaffold design and manufacturing: from concept to clinic

SJ Hollister - Advanced materials, 2009 - Wiley Online Library
Abstract Since Robert Langer and colleagues pioneered the concept of reconstructing tissue
using cells transplanted on synthetic polymer matrices in the early 1990s, research in the …

[HTML][HTML] Insights into the mechanics of solid conical microneedle array insertion into skin using the finite element method

W Shu, H Heimark, N Bertollo, DJ Tobin… - Acta Biomaterialia, 2021 - Elsevier
In order to develop optimum microneedle designs, researchers must first develop robust,
repeatable and adaptable test methods which are representative of in vivo conditions …

In vivo and in vitro evaluation of a biodegradable magnesium vascular stent designed by shape optimization strategy

C Chen, J Chen, W Wu, Y Shi, L Jin, L Petrini, L Shen… - Biomaterials, 2019 - Elsevier
The performance of biodegradable magnesium alloy stents (BMgS) requires special
attention to non-uniform residual stress distribution and stress concentration, which can …

The mechanical behavior of skin: Structures and models for the finite element analysis

JM Benítez, FJ Montáns - Computers & Structures, 2017 - Elsevier
Soft biological tissues are complex materials with a large structural variety, with differences
in behavior, but with some common characteristics. Skin is an archetypal soft tissue which …

Rupture of blood clots: Mechanics and pathophysiology

V Tutwiler, J Singh, RI Litvinov, JL Bassani… - Science …, 2020 - science.org
Fibrin is the three-dimensional mechanical scaffold of protective blood clots that stop
bleeding and pathological thrombi that obstruct blood vessels. Fibrin must be mechanically …