Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications
Ischemic stroke caused by arterial occlusion is the most common type of stroke, which is
among the most frequent causes of disability and death worldwide. Current treatment …
among the most frequent causes of disability and death worldwide. Current treatment …
Glial cells: role of the immune response in ischemic stroke
S Xu, J Lu, A Shao, JH Zhang, J Zhang - Frontiers in immunology, 2020 - frontiersin.org
Ischemic stroke, which accounts for 75–80% of all strokes, is the predominant cause of
morbidity and mortality worldwide. The post-stroke immune response has recently emerged …
morbidity and mortality worldwide. The post-stroke immune response has recently emerged …
Macrophage‐disguised manganese dioxide nanoparticles for neuroprotection by reducing oxidative stress and modulating inflammatory microenvironment in acute …
C Li, Z Zhao, Y Luo, T Ning, P Liu, Q Chen… - Advanced …, 2021 - Wiley Online Library
Reperfusion injury is still a major challenge that impedes neuronal survival in ischemic
stroke. However, the current clinical treatments are remained on single pathological …
stroke. However, the current clinical treatments are remained on single pathological …
Curcumin Ameliorates White Matter Injury after Ischemic Stroke by Inhibiting Microglia/Macrophage Pyroptosis through NF‐κB Suppression and NLRP3 …
Y Ran, W Su, F Gao, Z Ding, S Yang… - Oxidative medicine …, 2021 - Wiley Online Library
NLRP3 inflammasome‐mediated pyroptosis is a proinflammatory programmed cell death
pathway, which plays a vital role in functional outcomes after stroke. We previously …
pathway, which plays a vital role in functional outcomes after stroke. We previously …
[HTML][HTML] M2 microglia-derived exosomes protect the mouse brain from ischemia-reperfusion injury via exosomal miR-124
Rationale: Microglia play a critical role in modulating cell death and neurobehavioral
recovery in response to brain injury either by direct cell-cell interaction or indirect secretion …
recovery in response to brain injury either by direct cell-cell interaction or indirect secretion …
The predictive role of systemic inflammation response index (SIRI) in the prognosis of stroke patients
Y Zhang, Z Xing, K Zhou, S Jiang - Clinical interventions in aging, 2021 - Taylor & Francis
Purpose Stroke is a disease associated with high mortality. Many inflammatory indicators
such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte …
such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte …
Dual functions of microglia in ischemic stroke
C Qin, LQ Zhou, XT Ma, ZW Hu, S Yang, M Chen… - Neuroscience …, 2019 - Springer
Ischemic stroke is a leading cause of morbidity and mortality worldwide. Resident microglia
are the principal immune cells of the brain, and the first to respond to the pathophysiological …
are the principal immune cells of the brain, and the first to respond to the pathophysiological …
Microglia and inflammatory responses in diabetic retinopathy
UM Kinuthia, A Wolf, T Langmann - Frontiers in immunology, 2020 - frontiersin.org
Diabetic retinopathy is a vision-threatening disease affecting neurons and microvasculature
of the retina. The development of this disease is associated with the action of inflammatory …
of the retina. The development of this disease is associated with the action of inflammatory …
[HTML][HTML] Ischemia/reperfusion
T Kalogeris, CP Baines, M Krenz… - Comprehensive …, 2016 - ncbi.nlm.nih.gov
Ischemic disorders, such as myocardial infarction, stroke, and peripheral vascular disease,
are the most common causes of debilitating disease and death in westernized cultures. The …
are the most common causes of debilitating disease and death in westernized cultures. The …
Neuroinflammation in vascular cognitive impairment and dementia: current evidence, advances, and prospects
Z Tian, X Ji, J Liu - International Journal of Molecular Sciences, 2022 - mdpi.com
Vascular cognitive impairment and dementia (VCID) is a major heterogeneous brain
disease caused by multiple factors, and it is the second most common type of dementia in …
disease caused by multiple factors, and it is the second most common type of dementia in …