Drug resistance is a major problem in the treatment of cancer patients. Resistance can
develop after prolonged cycles of chemotherapy or can be present intrinsically in the patient …

OBJECTIVE: This review aims to provide a brief introduction to each major category of
available tools and algorithms for microRNA (miRNA) research, as well as to present some …

Chemoresistance is a major cause of recurrence and poor prognosis in triple-negative
breast cancer (TNBC) patients. The essential oil of Rhizoma Curcumae has been recently …

Abstract miRNAs (microRNAs) are frequently and aberrantly expressed in many cancers.
MiR-873 has been revealed to be downregulated in colorectal cancer and glioblastoma …

In this study, we examined the role of the miRNA miR-770-5p in cisplatin chemotherapy
resistance in ovarian cancer (OVC) patients. miR-770-5p expression was reduced in …

Accumulated evidence suggests that the Hippo signaling pathway plays crucial roles in
mammary gland development and breast cancer. Key components of the Hippo pathway …

MicroRNAs (miRNAs) regulate a wide range of cellular signaling pathways and biological
processes in both physiological and pathological states such as cancer. We have previously …

Estrogen receptor alpha (ERα), a nuclear transcription factor, is a well-validated therapeutic
target for more than 70% of all breast cancers (BCs). Antagonizing ERα either by selective …

Paclitaxel (PTX) is the front‑line chemotherapeutic agent against human non‑small cell lung
cancer (NSCLC). However, its therapeutic efficacy is restricted by the increasing frequency …

Chemoresistance is a major challenge to successful chemotherapy of ovarian cancer, which
represents the leading cause of mortality from gynecologic malignancies. We demonstrated …