Clinical trial principles and endpoint definitions for paravalvular leaks in surgical prosthesis

CE Ruiz, RT Hahn, A Berrebi, JS Borer… - European heart …, 2018 - academic.oup.com
Abstract The VARC (Valve Academic Research Consortium) for transcatheter aortic valve
replacement set the standard for selecting appropriate clinical endpoints reflecting safety …

Intracardiac echocardiography in structural heart disease interventions

M Alkhouli, ZM Hijazi, DR Holmes, CS Rihal… - JACC: Cardiovascular …, 2018 - jacc.org
Intracardiac echocardiography has historically been used to guide a limited number of
transcatheter cardiac interventions. However, the tremendous advances in structural heart …

Valve-in-valve TAVR: state-of-the-art review

JJ Edelman, JM Khan, T Rogers, C Shults… - …, 2019 - journals.sagepub.com
An increasing number of surgically implanted bioprostheses will require re-intervention for
structural valve deterioration. Valve-in-valve transcatheter aortic valve replacement (ViV …

Intracardiac versus transesophageal echocardiography to guide transcatheter closure of interatrial communications: nationwide trend and comparative analysis

F Alqahtani, A Bhirud, S Aljohani, J Mills… - Journal of …, 2017 - Wiley Online Library
Objectives This study aimed to assess current temporal trends in utilization of ICE versus
TEE guided closure of interatrial communications, and to compare periprocedural …

Cardiac prostheses‐related hemolytic anemia

M Alkhouli, A Farooq, RS Go, S Balla… - Clinical …, 2019 - Wiley Online Library
Hemolysis is an unintended sequel of temporary or permanent intracardiac devices.
However, limited data exist on the characteristics and treatment of hemolysis in patients with …

Successful percutaneous mitral paravalvular leak closure is associated with improved midterm survival

M Alkhouli, CJ Zack, M Sarraf, MF Eleid… - Circulation …, 2017 - Am Heart Assoc
Background—Percutaneous closure of prosthetic mitral valve paravalvular leak (PVL) has
emerged as an alternative to surgical treatment in high-risk patients. Limited data exist on …

Peridevice leak after left atrial appendage occlusion: incidence, mechanisms, clinical impact, and management

M Alkhouli, O De Backer, CR Ellis… - Cardiovascular …, 2023 - jacc.org
Left atrial appendage occlusion is an increasingly adopted stroke prevention strategy in
patients with atrial fibrillation. However, peridevice leaks after the procedure are not …

Meta-analysis comparing transcatheter and surgical treatments of paravalvular leaks

T Busu, F Alqahtani, V Badhwar, CC Cook… - The American Journal of …, 2018 - Elsevier
Percutaneous paravalvular leak (PVL) closure has emerged as a feasible alternative to redo
valve surgery. However, comparative data on percutaneous and surgical treatment of PVL …

Techniques and outcomes of paravalvular leak repair after transcatheter aortic valve replacement

TM Waterbury, GS Reeder, SV Pislaru… - Catheterization and …, 2017 - Wiley Online Library
Objectives To investigate the feasibility, procedural success, and outcomes of paravalvular
leak (PVL) closure in patients with prior transcatheter aortic valve replacement (TAVR) …

Structural heart disease emergencies

JC Jentzer, B Ternus, M Eleid… - Journal of Intensive …, 2021 - journals.sagepub.com
Structural heart disease (SHD) emergencies include acute deterioration of a stable lesion or
development of a new critical lesion. Structural heart disease emergencies can produce …