[HTML][HTML] Remodeling tumor microenvironment with natural products to overcome drug resistance
W Zhang, S Li, C Li, T Li, Y Huang - Frontiers in Immunology, 2022 - frontiersin.org
With cancer incidence rates continuing to increase and occurrence of resistance in drug
treatment, there is a pressing demand to find safer and more effective anticancer strategy for …
treatment, there is a pressing demand to find safer and more effective anticancer strategy for …
[HTML][HTML] Decoding the regulatory roles of non-coding RNAs in cellular metabolism and disease
Y Zong, X Wang, B Cui, X Xiong, A Wu, C Lin, Y Zhang - Molecular Therapy, 2023 - cell.com
Non-coding RNAs, including long non-coding RNAs (lncRNAs), microRNAs (miRNAs), and
circular RNAs (circRNAs), are being studied extensively in a variety of fields. Their roles in …
circular RNAs (circRNAs), are being studied extensively in a variety of fields. Their roles in …
MYC the oncogene from hell: Novel opportunities for cancer therapy
A Papadimitropoulou, M Makri, G Zoidis - European Journal of Medicinal …, 2024 - Elsevier
Cancer comprises a heterogeneous disease, characterized by diverse features such as
constitutive expression of oncogenes and/or downregulation of tumor suppressor genes …
constitutive expression of oncogenes and/or downregulation of tumor suppressor genes …
[HTML][HTML] The relationship between CD4+ T cell glycolysis and their functions
S Liu, S Liao, L Liang, J Deng, Y Zhou - Trends in Endocrinology & …, 2023 - cell.com
CD4+ T cells are effector T cells (Teffs) produced by the differentiation of initial T cells in
peripheral lymphoid tissue after being attacked by antigens, and have an indispensable role …
peripheral lymphoid tissue after being attacked by antigens, and have an indispensable role …
[HTML][HTML] MYC and MET cooperatively drive hepatocellular carcinoma with distinct molecular traits and vulnerabilities
C Sequera, M Grattarola, A Holczbauer, R Dono… - Cell Death & …, 2022 - nature.com
Enhanced activation of the transcription factor MYC and of the receptor tyrosine kinase MET
are among the events frequently occurring in hepatocellular carcinoma (HCC). Both genes …
are among the events frequently occurring in hepatocellular carcinoma (HCC). Both genes …
[HTML][HTML] Pharmacological inhibition of MYC to mitigate chemoresistance in preclinical models of squamous cell carcinoma
S Liu, Z Qin, Y Mao, N Wang, W Zhang, Y Wang… - Theranostics, 2024 - ncbi.nlm.nih.gov
Rationale: Cisplatin-based chemotherapy is the first-line treatment for late-stage head and
neck squamous cell carcinoma (HNSCC). However, resistance to cisplatin has become a …
neck squamous cell carcinoma (HNSCC). However, resistance to cisplatin has become a …
[HTML][HTML] C-myc expression in oral squamous cell carcinoma: molecular mechanisms in cell survival and cancer progression
GD Marconi, Y Della Rocca, L Fonticoli, F Melfi… - Pharmaceuticals, 2022 - mdpi.com
Oral squamous cell carcinoma (OSCC) represents 90% of malignant epithelial cancer that
occurs in the oral cavity. The c-Myc factor is expressed in multiple types of cancer …
occurs in the oral cavity. The c-Myc factor is expressed in multiple types of cancer …
[HTML][HTML] Advanced progress of spatial metabolomics in head and neck cancer research
H Zhao, C Shi, W Han, G Luo, Y Huang, Y Fu, W Lu… - Neoplasia, 2024 - Elsevier
Head and neck cancer ranks as the sixth most prevalent malignancy, constituting 5% of all
cancer cases. Its inconspicuous onset often leads to advanced stage diagnoses, prompting …
cancer cases. Its inconspicuous onset often leads to advanced stage diagnoses, prompting …
[HTML][HTML] Oncogenic KRAS mutation confers chemoresistance by upregulating SIRT1 in non-small cell lung cancer
DH Shin, JY Jo, M Choi, KH Kim, YK Bae… - Experimental & Molecular …, 2023 - nature.com
Kirsten rat sarcoma viral oncogene homologue (KRAS) is a frequent oncogenic driver of
solid tumors, including non-small cell lung cancer (NSCLC). The treatment and outcomes of …
solid tumors, including non-small cell lung cancer (NSCLC). The treatment and outcomes of …
LncRNA CCAT1 participates in pancreatic ductal adenocarcinoma progression by forming a positive feedback loop with c-Myc
C Cheng, Z Liu, D Liu, H Chen, Y Wang… - Carcinogenesis, 2024 - academic.oup.com
Long noncoding RNAs (lncRNAs) play fundamental roles in cancer development; however,
the underlying mechanisms for a large proportion of lncRNAs in pancreatic ductal …
the underlying mechanisms for a large proportion of lncRNAs in pancreatic ductal …