Background & Aims Liver stiffness measurement (LSM) by vibration-controlled transient
elastography (VCTE) has been shown to predict outcomes of patients with primary biliary …

Cholangiopathies encompass various biliary diseases affecting the biliary epithelium,
resulting in cholestasis, inflammation, fibrosis, and ultimately liver cirrhosis. Primary biliary …

Background and Aims The impact of sex on the postcirrhosis progression of primary biliary
cholangitis (PBC) has not been well defined. Prior studies have suggested that men have …

Background Obeticholic acid (OCA) and fibrates are second‐line therapies for patients with
primary biliary cholangitis (PBC) with an inadequate response to ursodeoxycholic acid …

Nanoceria with phosphatase-like behavior shows its great potential for many important
biological applications through a catalytic dephosphorylation process. Herein, we …

Primary biliary cirrhosis (PBC) is a chronic immune-mediated liver disease characterized by
progressive cholestasis, biliary fibrosis and eventually cirrhosis. It results in characteristic …

Background & Aims There are few data from longitudinal studies of trends in primary biliary
cholangitis (PBC) among patients under routine clinical care in the United States. We …

Primary biliary cholangitis (PBC) causes chronic and persistent cholestasis in the liver,
eventually resulting in cirrhosis and hepatic failure without appropriate treatment. PBC …

Background & Aims Obeticholic acid (OCA) is an agonist of the nuclear bile acid receptor
farnesoid X receptor, which regulates hepatic bile acid metabolism. We tested whether OCA …

We sought to identify factors that are predictive of liver transplantation or death in patients
with primary sclerosing cholangitis (PSC), and to develop and validate a contemporaneous …