Biological factors influencing depression in later life: role of aging processes and treatment implications
SM Szymkowicz, AR Gerlach, D Homiack… - Translational …, 2023 - nature.com
Late-life depression occurring in older adults is common, recurrent, and malignant. It is
characterized by affective symptoms, but also cognitive decline, medical comorbidity, and …
characterized by affective symptoms, but also cognitive decline, medical comorbidity, and …
[HTML][HTML] Investigating the effectiveness and tolerability of intranasal esketamine among older adults with treatment-resistant depression (TRD): a post-hoc analysis …
G d'Andrea, S Chiappini, RS McIntyre… - The American Journal of …, 2023 - Elsevier
Introduction Treatment-resistant depression (TRD) is a serious and debilitating psychiatric
disorder that frequently affects older patients. Esketamine nasal spray (ESK-NS) has …
disorder that frequently affects older patients. Esketamine nasal spray (ESK-NS) has …
Treatment-resistant late-life depression: a review of clinical features, neuropsychology, neurobiology, and treatment
S Subramanian, HA Oughli, MA Gebara… - Psychiatric …, 2023 - psych.theclinics.com
Treatment-Resistant Late-Life Depression - Psychiatric Clinics Skip to Main Content
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Treatment-Resistant Depression in Older Adults
DC Steffens - New England Journal of Medicine, 2024 - Mass Medical Soc
Key Clinical Points Treatment-Resistant Depression in Older Adults Treatment-resistant
depression is common in older adults with depression and is associated with several …
depression is common in older adults with depression and is associated with several …
Optimizing outcomes of treatment-resistant depression in older adults (OPTIMUM): study design and treatment characteristics of the first 396 participants randomized
Objective Evidence from clinical trials comparing effectiveness and safety of
pharmacological strategies in older adults unresponsive to first-line antidepressants is …
pharmacological strategies in older adults unresponsive to first-line antidepressants is …
Optimizing treatment for older adults with depression
M Srifuengfung, BRT Pennington… - Therapeutic Advances …, 2023 - journals.sagepub.com
This review presents a comprehensive guide for optimizing medication management in
older adults with depression within an outpatient setting. Medication optimization involves …
older adults with depression within an outpatient setting. Medication optimization involves …
Change in patient‐centered outcomes of psychological well‐being, sleep, and suicidality following treatment with intravenous ketamine for late‐life treatment‐resistant …
B Vanderschelden, MA Gebara… - … Journal of Geriatric …, 2023 - Wiley Online Library
Objective To examine whether psychological well‐being, sleep, and suicidality improved
with treatment with intravenous (IV) ketamine for late‐life treatment‐resistant depression …
with treatment with intravenous (IV) ketamine for late‐life treatment‐resistant depression …
Effect of prior pharmacotherapy on remission with sequential bilateral theta-burst versus standard bilateral repetitive transcranial magnetic stimulation in treatment …
RA Wathra, BH Mulsant, ZJ Daskalakis… - The British Journal of …, 2023 - cambridge.org
Repetitive transcranial magnetic stimulation (rTMS) is used for treatment of late-life
depression. In the FOUR-D study, sequential bilateral theta-burst stimulation (TBS) had …
depression. In the FOUR-D study, sequential bilateral theta-burst stimulation (TBS) had …
Towards outcome-driven patient subgroups: a machine learning analysis across six depression treatment studies
Background Major depressive disorder (MDD) is a heterogeneous condition; multiple
underlying neurobiological and behavioral substrates are associated with treatment …
underlying neurobiological and behavioral substrates are associated with treatment …