[HTML][HTML] Osteoporosis pathogenesis and treatment: existing and emerging avenues
B Liang, G Burley, S Lin, YC Shi - Cellular & Molecular Biology Letters, 2022 - Springer
Osteoporotic fractures lead to increased disability and mortality in the elderly population.
With the rapid increase in the aging population around the globe, more effective treatments …
With the rapid increase in the aging population around the globe, more effective treatments …
miRNAs as potential game-changers in bone diseases: Future medicinal and clinical Uses
AS Doghish, MS Elballal, O Elazazy… - … -Research and Practice, 2023 - Elsevier
Abstract MicroRNAs (miRNAs), short, highly conserved non-coding RNA, influence gene
expression by sequential mechanisms such as mRNA breakdown or translational …
expression by sequential mechanisms such as mRNA breakdown or translational …
[HTML][HTML] Calcium phosphate nanoparticles for therapeutic applications in bone regeneration
TJ Levingstone, S Herbaj, NJ Dunne - Nanomaterials, 2019 - mdpi.com
Bone injuries and diseases constitute a burden both socially and economically, as the
consequences of a lack of effective treatments affect both the patients' quality of life and the …
consequences of a lack of effective treatments affect both the patients' quality of life and the …
Materials science and design principles of growth factor delivery systems in tissue engineering and regenerative medicine
R Subbiah, RE Guldberg - Advanced healthcare materials, 2019 - Wiley Online Library
Growth factors (GFs) are signaling molecules that direct cell development by providing
biochemical cues for stem cell proliferation, migration, and differentiation. GFs play a key …
biochemical cues for stem cell proliferation, migration, and differentiation. GFs play a key …
[HTML][HTML] The role of micro RNA and long-non-coding RNA in osteoporosis
NY Ko, LR Chen, KH Chen - International Journal of Molecular Sciences, 2020 - mdpi.com
Osteoporosis is a major concern worldwide and can be attributed to an imbalance between
osteoblastic bone formation and osteoclastic bone resorption due to the natural aging …
osteoblastic bone formation and osteoclastic bone resorption due to the natural aging …
[HTML][HTML] The role of miR-21 in osteoblasts–osteoclasts coupling in vitro
A Smieszek, K Marcinkowska, A Pielok, M Sikora… - Cells, 2020 - mdpi.com
MiR-21 is being gradually more and more recognized as a molecule regulating bone tissue
homeostasis. However, its function is not fully understood due to the dual role of miR-21 on …
homeostasis. However, its function is not fully understood due to the dual role of miR-21 on …
Promoting osteogenic differentiation of human adipose‐derived stem cells by altering the expression of exosomal miRNA
S Yang, S Guo, S Tong, X Sun - Stem Cells International, 2019 - Wiley Online Library
Human adipose‐derived stem cells (ADSCs) can release exosomes; however, their specific
functions remain elusive. In this study, we verified that exosomes derived from …
functions remain elusive. In this study, we verified that exosomes derived from …
[HTML][HTML] Calcium phosphate nanoparticles-based systems for RNAi delivery: Applications in bone tissue regeneration
Bone-related injury and disease constitute a significant global burden both socially and
economically. Current treatments have many limitations and thus the development of new …
economically. Current treatments have many limitations and thus the development of new …
[HTML][HTML] MiRNAs expression modulates osteogenesis in response to exercise and nutrition
In recent years, many articles have been published describing the impact of physical activity
and diet on bone health. This review has aimed to figure out the possible epigenetic …
and diet on bone health. This review has aimed to figure out the possible epigenetic …
[HTML][HTML] Roles of MicroRNAs in osteogenesis or adipogenesis differentiation of bone marrow stromal progenitor cells
Bone marrow stromal cells (BMSCs) are multipotent cells which can differentiate into
chondrocytes, osteoblasts, and fat cells. Under pathological stress, reduced bone formation …
chondrocytes, osteoblasts, and fat cells. Under pathological stress, reduced bone formation …