Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …

Abstract Sepsis-associated encephalopathy (SAE), a common neurological complication of
sepsis, is a heterogenous complex clinical syndrome caused by the dysfunctional response …

Sepsis is a manifestation of the immune and inflammatory response to infection, which may
lead to multi‑organ failure. Health care advances have improved outcomes in critical illness …

Substance P (SP), encoded by the TAC1/Tac1 gene, acts as a significant mediator in
dysregulated systemic inflammatory response and associated organ injury in sepsis by …

The hospital mortality in patients with ST-segment elevation myocardial infarction (STEMI) is
about 6% and has not decreased in recent years. The leading cause of death of these …

Abstract Ethnopharmacological relevance Exocarpium Citri Grandis (ECG), the epicarp of C.
grandis 'Tomentosa'which is also known as Hua-Ju-Hong in China, has been widely used …

Low molecular weight heparins (LMWHs) are derived from heparin through chemical or
enzymatic cleavage with an average molecular weight (Mw) of 2000–8000 Da. They exhibit …

Objective We investigated the toxicological mechanism by which perfluorooctane sulfonate
(PFOS) induces liver injury via ferroptosis. Methods Primary mouse hepatocytes were …

The development of drug resistance remains a major challenge in cancer treatment.
Ferroptosis, a unique type of regulated cell death, plays a pivotal role in inhibiting tumour …

Neonatal hypoxia-ischemia encephalopathy (NHIE), an oxygen deprivation-mediated brain
injury due to birth asphyxia or reduced cerebral blood perfusion, often leads to lifelong …