Gut microbiota-derived fatty acid and sterol metabolites: biotransformation and immunomodulatory functions

H Zhang, Y Xie, F Cao, X Song - Gut Microbes, 2024 - Taylor & Francis
Commensal microorganisms in the human gut produce numerous metabolites by using
small molecules derived from the host or diet as precursors. Host or dietary lipid molecules …

The gut microbiome in disorders of gut–brain interaction

N Kraimi, T Ross, J Pujo, G De Palma - Gut Microbes, 2024 - Taylor & Francis
Functional gastrointestinal disorders (FGIDs), chronic disorders characterized by either
abdominal pain, altered intestinal motility, or their combination, have a worldwide …

Effects of salidroside on atherosclerosis: potential contribution of gut microbiota

SF Fei, C Hou, F Jia - Frontiers in Pharmacology, 2024 - frontiersin.org
Much research describes gut microbiota in atherosclerotic cardiovascular diseases
(ASCVD) for that the composition of the intestinal microbiome or its metabolites can directly …

From the unknown to spotlight: newly identified hormone adjusts hepatic cholesterol synthesis to dietary uptake

YB Nkeh, RG Elgin, G Saher - Signal Transduction and Targeted …, 2024 - nature.com
In a study published in Cell, Hu and colleagues discovered that the signaling activity of the
intestinal hormone Cholesin leads to the attenuation of hepatic cholesterol synthesis in …

[HTML][HTML] Evaluating the effects of corn flour product consumption on cardio-metabolic outcomes and the gut microbiota in adults with elevated cholesterol: A …

B Liedike, M Khatib, B Tabarsi, M Harris, SL Wilson… - The Journal of …, 2024 - Elsevier
Background Consumption of whole grains is associated with a reduction in chronic diseases
and offers benefits for cardiovascular health and metabolic regulation. The relationship …

Digestive dynamics: Unveiling interplay between the gut microbiota and the liver in macronutrient metabolism and hepatic metabolic health

MR Kandalgaonkar, V Kumar… - Physiological …, 2024 - Wiley Online Library
Although the liver is the largest metabolic organ in the body, it is not alone in functionality
and is assisted by “an organ inside an organ,” the gut microbiota. This review attempts to …

[HTML][HTML] Association of lipid-lowering drugs with gut microbiota: a Mendelian randomization study

L Shi, X Liu, E Li, S Zhang, A Zhou - Journal of Clinical Lipidology, 2024 - Elsevier
Background The gut microbiota can be influenced by lipid metabolism. We aimed to
evaluate the impact of lipid-lowering medications, such as proproteinconvertase …

Genetic screening and metabolomics identify glial adenosine metabolism as a therapeutic target in Parkinson's disease

MJ Sodders, J Avila-Pacheco, E Okorie, M Shen… - bioRxiv, 2024 - biorxiv.org
Parkinson's disease (PD) is the second most common neurodegenerative disorder and
lacks disease-modifying therapies. We developed a Drosophila model for identifying novel …

Multi-omic links between gut microbiome and cardiovascular disease

J Hindson - Nature Reviews Gastroenterology & Hepatology, 2024 - nature.com
The Framingham Heart Study is an ongoing observational cohort study to identify risk factors
for cardiovascular disease. Xavier and colleagues used data from study participants to …

Gut bacteria can break down cholesterol

I Fernández-Ruiz - Nature Reviews Cardiology, 2024 - nature.com
Gut bacteria can break down cholesterol | Nature Reviews Cardiology Skip to main content
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