Molecular mechanism of cognitive impairment associated with Parkinson's disease: A stroke perspective

S Gupta, J Khan, S Ghosh - Life Sciences, 2023 - Elsevier
Parkinson's disease (PD) is a common neurological illness that causes several motor and
non-motor symptoms, most characteristically limb tremors and bradykinesia. PD is a slowly …

[HTML][HTML] The Dual Role of Autophagy in Postischemic Brain Neurodegeneration of Alzheimer's Disease Proteinopathy

R Pluta - International Journal of Molecular Sciences, 2023 - mdpi.com
Autophagy is a self-defense and self-degrading intracellular system involved in the recycling
and elimination of the payload of cytoplasmic redundant components, aggregated or …

[HTML][HTML] LRP1 and RAGE Genes Transporting Amyloid and Tau Protein in the Hippocampal CA3 Area in an Ischemic Model of Alzheimer's Disease with 2-Year …

R Pluta, J Kocki, J Bogucki, A Bogucka-Kocka… - Cells, 2023 - mdpi.com
Explaining changes at the gene level that occur during neurodegeneration in the CA3 area
is crucial from the point of view of memory impairment and the development of post-ischemic …

[HTML][HTML] Receptor-interacting protein kinase 2 (RIPK2) profoundly contributes to post-stroke neuroinflammation and behavioral deficits with microglia as unique …

J Larochelle, RJ Tishko, C Yang, Y Ge, LT Phan… - Journal of …, 2023 - Springer
Background Receptor-interacting protein kinase 2 (RIPK2) is a serine/threonine kinase
whose activity propagates inflammatory signaling through its association with pattern …

[HTML][HTML] Apitherapy in Post-Ischemic Brain Neurodegeneration of Alzheimer's Disease Proteinopathy: Focus on Honey and Its Flavonoids and Phenolic Acids

R Pluta, B Miziak, SJ Czuczwar - Molecules, 2023 - mdpi.com
Neurodegeneration of the brain after ischemia is a major cause of severe, long-term
disability, dementia, and mortality, which is a global problem. These phenomena are …

Neuroanatomical correlates of cognitive impairment following basal ganglia-thalamic post-hemorrhagic stroke: Uncovering network-wide alterations in hemispheric …

H Wang, M Yu, J Ren, X Zhong, D Xu, L Gao, H Xu - Brain Research, 2023 - Elsevier
Cognitive impairment and recovery are central issues in hemorrhagic stroke. This study
aimed to investigate whether post-hemorrhagic stroke cognitive impairment (PhSCI) is …

Imaging biomarkers of VCI: a focused update

U Clancy, AK Kancheva, MCV Hernández… - Stroke, 2024 - journals.lww.com
Vascular cognitive impairment is common after stroke, in memory clinics, medicine for the
elderly services, and undiagnosed in the community. Vascular disease is said to be the …

Infection, inflammation, and poststroke cognitive impairment

E Milosevich, N Demeyere… - Journal of the American …, 2024 - Am Heart Assoc
Background Infection and inflammation are dementia risk factors in population‐based
cohorts; however, studies in stroke are scarce. We determined the prevalence of infection …

[HTML][HTML] Cell autonomous role of border associated macrophages in ApoE4 neurovascular dysfunction and susceptibility to white matter injury

C Iadecola, A Anfray, S Schaeffer, Y Hattori… - Research …, 2023 - ncbi.nlm.nih.gov
Abstract Apolipoprotein-E4 (ApoE4), the strongest genetic risk factor for sporadic
Alzheimer's disease, is also a risk factor for microvascular pathologies leading to cognitive …

Hyponatremia as a predictor of cognitive deterioration in hospitalized post-stroke patients

Y Yoshimura, H Wakabayashi, F Nagano… - Journal of Clinical …, 2024 - Elsevier
Purpose Evidence is scarce regarding the association between hyponatremia and
alterations in cognitive function among hospitalized older patients. We aimed to investigate …