[HTML][HTML] Nrf2 for a key member of redox regulation: A novel insight against myocardial ischemia and reperfusion injuries

X Han, H Wang, F Du, X Zeng, C Guo - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Nuclear factor erythroid-2 related factor 2 (Nrf2), a nuclear transcription factor, modulates
genes responsible for antioxidant responses against toxic and oxidative stress to maintain …

Cardiac-targeting peptide: from discovery to applications

D Sahagun, M Zahid - Biomolecules, 2023 - mdpi.com
Despite significant strides in prevention, diagnosis, and treatment, cardiovascular diseases
remain the number one cause of mortality in the United States, with rates climbing at an …

Galangin attenuates myocardial ischemic reperfusion-induced ferroptosis by targeting Nrf2/Gpx4 signaling pathway

T Yang, H Liu, C Yang, H Mo, X Wang… - Drug Design …, 2023 - Taylor & Francis
Purpose Myocardial ischemic reperfusion injury (MIRI) is a crucial clinical problem globally.
The molecular mechanisms of MIRI need to be fully explored to develop new therapeutic …

Engineered bone marrow mesenchymal stem cell-derived exosomes loaded with miR302 through the cardiomyocyte specific peptide can reduce myocardial ischemia …

J Gu, J You, H Liang, J Zhan, X Gu, Y Zhu - Journal of Translational …, 2024 - Springer
Background MicroRNA (miRNA)-based therapies have shown great potential in myocardial
repair following myocardial infarction (MI). MicroRNA-302 (miR302) has been reported to …

Activated Immune System Determines In Vivo Anti‐Tumor Effect of Phototherapy by Inhibiting Cancer‐Associated Fibroblasts

M Ding, H Chen, CF Guimarães… - Advanced Functional …, 2024 - Wiley Online Library
Immune activation has been widely recognized to promote anti‐tumor effects in vivo.
However, in previous anti‐tumor studies of combined photo/immunotherapy, the tumor …

[HTML][HTML] Short-term effects of ambient gaseous air pollution on blood platelet mitochondrial DNA methylation and myocardial ischemia

Y Jiang, J Chen, L Guo, Y Lan, G Li, Q Liu, H Li… - Environment …, 2024 - Elsevier
Background The potential effects of short-term exposure to major ambient gaseous
pollutants (ozone: O 3, carbon monoxide: CO, and sulfur dioxide: SO 2) on platelet …

The role of ligands on synthesis, functional control, and biomedical applications of near-infrared light-responsive metal-based nanoparticles

X Hu, P Wang, C Huang, C Fang, F Li, D Ling - Coordination Chemistry …, 2024 - Elsevier
Near-infrared light-responsive metal-based nanoparticles (NLMPs) have attracted
increasing attention recently due to their unique optical properties for biomedical …

Versatile Design of NO‐Generating Proteolipid Nanovesicles for Alleviating Vascular Injury

Y Yang, X Zhang, H Yan, R Zhao, R Zhang… - Advanced …, 2024 - Wiley Online Library
Vascular injury is central to the pathogenesis and progression of cardiovascular diseases,
however, fostering alternative strategies to alleviate vascular injury remains a persisting …

[HTML][HTML] Mitochondria-engine with self-regulation to restore degenerated intervertebral disc cells via bioenergetic robust hydrogel design

J Wang, Y Jiang, C Zhu, Z Liu, L Qi, H Ding, J Wang… - Bioactive Materials, 2024 - Elsevier
Previous studies have confirmed that intervertebral disc degeneration (IDD) is closely
associated with inflammation-induced reactive oxygen species (ROS) and resultant cell …

[HTML][HTML] ROS-responsive & scavenging NO nanomedicine for vascular diseases treatment by inhibiting endoplasmic reticulum stress and improving NO bioavailability

J Li, J Zhang, P Yu, H Xu, M Wang, Z Chen, B Yu… - Bioactive Materials, 2024 - Elsevier
Vascular diseases seriously threaten human life and health. Exogenous delivery of nitric
oxide (NO) represents an effective approach for maintaining vascular homeostasis during …