Accumulating evidence demonstrates that metabolic changes in the brain associated with
neuroinflammation, oxidative stress, and mitochondrial dysfunction play an important role in …

Age is the main risk factor for a number of human diseases, including neurodegenerative
disorders such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral …

Background Extant data from in vivo animal models and postmortem studies indicate that
Alzheimer's disease (AD) pathology is associated with reduction of the brain antioxidant …

Alzheimer's disease (AD) is the most common form of dementia in the elderly, with
increasing prevalence and no disease‐modifying treatment available yet. A remarkable …

Background There is growing evidence that Alzheimer disease (AD) is a pervasive
metabolic disorder with dysregulation in multiple biochemical pathways underlying its …

GSH plays an important role during the onset and progression of neuropsychiatric and
neurodegenerative diseases. GSH redox imbalance may be a primary cause of these brain …

We review the transport, synthesis and catabolism of glutathione in the brain as well as its
compartmentation and biochemistry in different brain cells. The major reactions involving …

Soccer is played by more than 250 million people worldwide. Repeatedly heading the ball
may place soccer players at high risk for repetitive subconcussive head impacts (RSHI). This …

Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases with
motor disturbances, cognitive decline, and behavioral impairment. It is characterized by the …

With millions of older individuals presently suffering from Alzheimer's disease (AD)
worldwide, AD is an unduly common form of dementia that exacts a heavy toll on affected …