RNA-binding proteins and cancer metastasis
S Wang, Z Sun, Z Lei, HT Zhang - Seminars in cancer biology, 2022 - Elsevier
RNA-binding proteins (RBPs) can regulate gene expression through post-transcriptionally
influencing all manner of RNA biology, including alternative splicing (AS), polyadenylation …
influencing all manner of RNA biology, including alternative splicing (AS), polyadenylation …
RNA-binding proteins in regulating mRNA stability and translation: roles and mechanisms in cancer
ABSTRACT RNA-binding proteins (RBPs) are key players in cellular physiology through
posttranscriptional regulation of the expression of target RNA transcripts. By modulating the …
posttranscriptional regulation of the expression of target RNA transcripts. By modulating the …
RNA-binding proteins in cancer: functional and therapeutic perspectives
D Kang, Y Lee, JS Lee - Cancers, 2020 - mdpi.com
Simple Summary RNA-binding proteins (RBPs) play central roles in regulating
posttranscriptional expression of genes. Many of them are known to be deregulated in a …
posttranscriptional expression of genes. Many of them are known to be deregulated in a …
[HTML][HTML] Deliver the promise: RNAs as a new class of molecular entities for therapy and vaccination
The concepts of developing RNAs as new molecular entities for therapies have arisen again
and again since the discoveries of antisense RNAs, direct RNA-protein interactions …
and again since the discoveries of antisense RNAs, direct RNA-protein interactions …
[HTML][HTML] RNA binding proteins (RBPs) and their role in DNA damage and radiation response in cancer
Traditionally majority of eukaryotic gene expression is influenced by transcriptional and post-
transcriptional events. Alterations in the expression of proteins that act post-transcriptionally …
transcriptional events. Alterations in the expression of proteins that act post-transcriptionally …
Epigenetic modification of CSDE1 locus dictates immune recognition of nascent tumorigenic cells
J Lv, Y Zhou, N Zhou, Z Wang, J Chen… - Science translational …, 2023 - science.org
Weak immunogenicity of tumor cells is a root cause for the ultimate failure of
immunosurveillance and immunotherapy. Although tumor evolution can be shaped by …
immunosurveillance and immunotherapy. Although tumor evolution can be shaped by …
RNA-binding proteins as important regulators of long non-coding RNAs in cancer
The majority of the genome is transcribed into pieces of non-(protein) coding RNA, among
which long non-coding RNAs (lncRNAs) constitute a large group of particularly versatile …
which long non-coding RNAs (lncRNAs) constitute a large group of particularly versatile …
First small-molecule inhibitors targeting the RNA-binding protein IGF2BP2/IMP2 for cancer therapy
C Dahlem, A Abuhaliema, SM Kessler… - ACS chemical …, 2022 - ACS Publications
The RNA-binding protein IGF2BP2/IMP2/VICKZ2/p62 is overexpressed in several tumor
entities, promotes tumorigenesis and tumor progression, and has been suggested to worsen …
entities, promotes tumorigenesis and tumor progression, and has been suggested to worsen …
RNA-binding proteins and their role in kidney disease
L Seufert, T Benzing, M Ignarski… - Nature Reviews …, 2022 - nature.com
RNA-binding proteins (RBPs) are of fundamental importance for post-transcriptional gene
regulation and protein synthesis. They are required for pre-mRNA processing and for RNA …
regulation and protein synthesis. They are required for pre-mRNA processing and for RNA …
RNA-binding proteins hold key roles in function, dysfunction, and disease
S Kelaini, C Chan, VA Cornelius, A Margariti - Biology, 2021 - mdpi.com
Simple Summary Chronic hyperglycemia manifests in a variety of different micro-and
macrovascular disorders such as diabetes mellitus and cardiovascular disease and has …
macrovascular disorders such as diabetes mellitus and cardiovascular disease and has …