[HTML][HTML] Antiseizure medication in early nervous system development. Ion channels and synaptic proteins as principal targets
PA Castro, I Pinto-Borguero, GE Yévenes… - Frontiers in …, 2022 - frontiersin.org
The main strategy for the treatment of epilepsy is the use of pharmacological agents known
as antiseizure medication (ASM). These drugs control the seizure onset and improves the …
as antiseizure medication (ASM). These drugs control the seizure onset and improves the …
The evolution of antiseizure medication therapy selection in adults: Is artificial intelligence-assisted antiseizure medication selection ready for prime time?
CL Gunasekera, JI Sirven… - Journal of Central …, 2023 - journals.sagepub.com
Antiseizure medications (ASMs) are the mainstay of symptomatic epilepsy treatment. The
primary goal of pharmacotherapy with ASMs in epilepsy is to achieve complete seizure …
primary goal of pharmacotherapy with ASMs in epilepsy is to achieve complete seizure …
[HTML][HTML] Increasing use of newer antiseizure medication during pregnancy: An observational study with special focus on lacosamide
M Hoeltzenbein, S Slimi, AK Fietz, R Stegherr… - Seizure, 2023 - Elsevier
Introduction Epilepsy is a common neurological disease requiring long-term therapy also
during pregnancy. Most studies on pregnancy outcomes in women with epilepsy are based …
during pregnancy. Most studies on pregnancy outcomes in women with epilepsy are based …
[HTML][HTML] Intravenous topiramate for seizure emergencies–first in human case report
L Apostolakopoulou, PB Varela, F Rossini… - Epilepsy & Behavior, 2023 - Elsevier
Topiramate (TPM) is widely used in focal and generalized epilepsies. It is commercially
available as tablets and sprinkles capsules for oral treatment. Previous studies comparing …
available as tablets and sprinkles capsules for oral treatment. Previous studies comparing …
Levetiracetam vs lamotrigine as first-line antiseizure medication in female patients with idiopathic generalized epilepsy
Importance After the recent limitations to prescribing valproate, many studies have
highlighted the challenging management of female patients of reproductive age with …
highlighted the challenging management of female patients of reproductive age with …
Antiepileptic drugs are endocrine disruptors for the human fetal testis ex vivo
L Lesné, C Desdoits-Lethimonier, E Hug… - Toxicological …, 2023 - academic.oup.com
Valproic acid (VPA) has long been the most widely used antiepileptic drug (AED) for the
treatment of epilepsy, bipolar psychiatric disorders, and migraine. However, long-term VPA …
treatment of epilepsy, bipolar psychiatric disorders, and migraine. However, long-term VPA …
Perampanel for the treatment of people with idiopathic generalized epilepsy in clinical practice
E Trinka, T Alsaadi, H Goji, T Maehara, S Takahashi… - …, 2023 - Wiley Online Library
Objective This study was undertaken to evaluate perampanel (PER) when used under real‐
world conditions to treat people with idiopathic generalized epilepsy (IGE) included in the …
world conditions to treat people with idiopathic generalized epilepsy (IGE) included in the …
Depression treatment in pregnancy: is it safe, or is it not?
V Gallitelli, R Franco, S Guidi, L Puri… - International journal of …, 2024 - mdpi.com
Prenatal depression carries substantial risks for maternal and fetal health and increases
susceptibility to postpartum depression. Untreated depression in pregnancy is correlated …
susceptibility to postpartum depression. Untreated depression in pregnancy is correlated …
The impact of pregnancy-related hormonal and physiological changes on antiseizure medications: expert perspective
D Li, S Franco, PB Pennell - Expert Review of Clinical …, 2024 - Taylor & Francis
Introduction Epilepsy is a disorder of recurrent, unprovoked seizures affecting approximately
15 million individuals of childbearing potential worldwide. Patients with epilepsy rely on …
15 million individuals of childbearing potential worldwide. Patients with epilepsy rely on …
[HTML][HTML] Presynaptic antiseizure medications-basic mechanisms and clues for their rational combinations
EK Czapińska-Ciepiela, J Łuszczki, P Czapiński… - Pharmacological …, 2024 - Springer
Among clinically highly efficient antiseizure medications (ASMs) there are modifiers of the
presynaptic release machinery. Of them, levetiracetam and brivaracetam show a high affinity …
presynaptic release machinery. Of them, levetiracetam and brivaracetam show a high affinity …