It has become increasingly clear that the simple neurodevelopmental model fails to explain
many aspects of schizophrenia including the timing of the onset, and the nature of the …

Animal models are critical for the study of psychiatric disorders since they allow the use of
invasive methods that cannot be used for ethical reasons in humans. Currently there are …

Schizophrenia is an aetiologically complex disorder arising from the interaction of a range of
factors acting at various stages of life. Schizophrenic individuals inherit genes that cause …

Objective: To evaluate predictors of treatment discontinuation against medical advice and
poor medication adherence among first-episode patients treated with olanzapine …

Various lines of evidence indicate the presence of progressive pathophysiological
processes occurring within the brains of patients with schizophrenia. By modulating …

Background Cognitive deficits are a characteristic feature of schizophrenia and contribute to
the profound disabilities associated with this illness. Some of the cognitive deficits that occur …

Mental health advocates and policy makers are increasingly attuned to the importance of the
recovery concept, and psychiatrists and neuroscientists increasingly emphasize the medical …

Introduction. Deficits in emotion perception and social skill have been well established in
schizophrenia; however, little is known about the extent of these deficits across the course of …

Results from clinical and imaging studies provide evidence for changes in schizophrenia
with disease progression, however, the underlying molecular differences that may occur at …

The neurodevelopmental hypothesis (NDH) of schizophrenia suggests that a disruption of
brain development during early life underlies the later emergence of psychosis during …