Context Individuals experiencing prodromal symptoms of schizophrenia (ultra-high-risk
group) demonstrate impaired performance on tasks of executive function, attention, and …

Schizophrenia is a disorder of a neurodevelopmental origin manifested symptomatically
after puberty. Structural neuroimaging studies show that neuroanatomical aberrations …

Although most patients who experience a first-episode of psychosis achieve remission of
positive psychotic symptoms, relapse is common. Existing relapse evaluation strategies are …

BACKGROUND: Many patients recovering from a first psychotic episode will discontinue
medication against medical advice, even before a 1-year treatment course is completed …

BackgroundDuration of untreated psychosis (DUP) may contribute to the observed
heterogeneity of the treatment response in first-episode schizophrenia. AimsTo examine the …

Abstract Disrupted in Schizophrenia 1 (DISC1) was identified as a potential susceptibility
gene for schizophrenia due to its disruption by a balanced t (1; 11)(q42; q14) translocation …

Social-cognitive deficits contribute to poor functional outcomes in early psychosis; however,
no effective pharmacological treatments exist for these problems. This study was the first to …

In schizophrenia spectrum disorders, improvement in symptoms varies between patients
with short and long durations of illness. In this meta-analysis we provided an overview of …

Homer proteins are involved in the functional assembly of postsynaptic density proteins at
glutamatergic synapses and are implicated in learning, memory and drug addiction. Here …

Abstract Cocaine Use Disorder (CUD) is a significant public health problem associated with
elevated morbidity and mortality within the United States. Current behavioral treatments …