A comprehensive review of the body of genetic studies on schizophrenia seems even more
daunting than the battle a psychiatrist wages daily in the office with her archenemy of a …

Oxidative stress and reduced brain levels of glutathione have been implicated in
schizophrenia and bipolar disorder. N-acetyl cysteine (NAC) is a precursor of glutathione …

Despite great progress in basic schizophrenia research, the conclusive identification of
specific etiological factors or pathogenic processes in the illness has remained elusive. The …

Clinical staging improved the possibility of intervening during the psychosis prodrome to
limit progression of illness. The current study aimed to validate a novel 4-stage severity …

Patients with first-episode schizophrenia frequently relapse during the first years of the
illness. This may be associated with clinical deterioration. It is important to prevent relapses …

Although the medial prefrontal cortex (mpFC) appears to constrain stress responses, indirect
evidences suggest that it might determine the stress response of the mesoaccumbens …

The neurodevelopmental hypothesis of schizophrenia posits an interaction between multiple
susceptibility genes and one or more environmental insults in early life, resulting in altered …

The primary objective of this study was to evaluate how schizophrenia (SCH) spectrum
disorders and applied antipsychotic (AP) treatment affect serum level of amino acids (AAs) …

Rationale There is evidence pointing to an association between prenatal exposure to
infection and increased liability to schizophrenia, and it has been suggested that the …

This systematic review and meta-analysis examined predictors of successful antipsychotic
dose reduction in schizophrenia. Prospective clinical trials and randomized controlled trials …