Compact point-detection fluorescence spectroscopy system for quantifying intrinsic fluorescence redox ratio in brain cancer diagnostics

Q Liu, G Grant, J Li, Y Zhang, F Hu, S Li… - … of biomedical optics, 2011 - spiedigitallibrary.org
We report the development of a compact point-detection fluorescence spectroscopy system
and two data analysis methods to quantify the intrinsic fluorescence redox ratio and …

Multimodal optical analysis discriminates freshly extracted human sample of gliomas, metastases and meningiomas from their appropriate controls

M Zanello, F Poulon, J Pallud, P Varlet, H Hamzeh… - Scientific reports, 2017 - nature.com
Delineating tumor margins as accurately as possible is of primordial importance in surgical
oncology: extent of resection is associated with survival but respect of healthy surrounding …

Combined autofluorescence and diffuse reflectance for brain tumour surgical guidance: initial ex vivo study results

H Lu, K Grygoryev, N Bermingham… - Biomedical Optics …, 2021 - opg.optica.org
This ex vivo study was conducted to assess the potential of using a fibre optic probe system
based on autofluorescence and diffuse reflectance for tissue differentiation in the brain. A …

Dysplasia and tumor discrimination in brain tissues by combined fluorescence, Raman, and diffuse reflectance spectroscopies

E Baria, F Giordano, R Guerrini, C Caporalini… - Biomedical Optics …, 2023 - opg.optica.org
Identification of neoplastic and dysplastic brain tissues is of paramount importance for
improving the outcomes of neurosurgical procedures. This study explores the combined …

Fluorescence spectroscopy as an efficient tool for staging the degree of liver fibrosis: an in vivo comparison with MRI

SS Nazeer, A Saraswathy, SJ Shenoy, RS Jayasree - Scientific Reports, 2018 - nature.com
The study utilizes autofluorescence spectroscopy (AFS) along with multivariate spectral
analysis for differentiating various stages of hepatic fibrosis. AFS has recently emerged as …

Multimodal optical analysis of meningioma and comparison with histopathology

M Zanello, F Poulon, P Varlet, F Chretien… - Journal of …, 2017 - Wiley Online Library
Meningioma is the most frequent primary central nervous system tumor. The risk of
recurrence and the prognosis are correlated with the extent of the resection that ideally …

AI-Powered Biomolecular-Specific and Label-Free Multispectral Imaging Rapidly Detects Malignant Neoplasm in Surgically Excised Breast Tissue Specimens

R Pandey, D Fournier, G Root… - … of Pathology & …, 2023 - meridian.allenpress.com
Context.—Repeated surgery is necessary for 20% to 40% of breast conservation surgeries
owing to the unavailability of any adjunctive, accurate, and objective tool in the surgeon's …

Noninvasive assessment of the risk of tobacco abuse in oral mucosa using fluorescence spectroscopy: a clinical approach

SS Nazeer, R Asish, C Venugopal… - Journal of …, 2014 - spiedigitallibrary.org
Tobacco abuse and alcoholism cause cancer, emphysema, and heart disease, which
contribute to high death rates, globally. Society pays a significant cost for these habits whose …

[HTML][HTML] Dual-modality optical diagnosis for precise in vivo identification of tumors in neurosurgery

M Zhu, W Chang, L Jing, Y Fan, P Liang, X Zhang… - Theranostics, 2019 - ncbi.nlm.nih.gov
In neurosurgery, the precise diagnosis and treatment of tumor diseases are challenging to
realize. Current clinical diagnoses lack fast and accurate intraoperative information …

Silicon Photomultiplier—A high dynamic range, high sensitivity sensor for bio-photonics applications

R Georgel, K Grygoryev, S Sorensen, H Lu… - Biosensors, 2022 - mdpi.com
This work is an overview of silicon photomultipliers (SiPMs) with a view to defining their
importance for bio-photonic and clinical applications. SiPMs are benchmarked against other …