Oxytocin and eating disorders: Knowledge gaps and future directions

J Russell, GE Hunt - Psychoneuroendocrinology, 2023 - Elsevier
Eating disorders continue to be a major public health issue and important cause of morbidity
and premature mortality, particularly for young people. Yet in a concerning dialectic, this …

Sniffing oxytocin: Nose to brain or nose to blood?

S Yao, Y Chen, Q Zhuang, Y Zhang, C Lan, S Zhu… - Molecular …, 2023 - nature.com
In recent years ample studies have reported that intranasal administration of the
neuropeptide oxytocin can facilitate social motivation and cognition in healthy and clinical …

Oxytocin administration enhances pleasantness and neural responses to gentle stroking but not moderate pressure social touch by increasing peripheral …

Y Chen, H Zou, X Hou, C Lan, J Wang, Y Qing, W Chen… - Elife, 2023 - elifesciences.org
Background: Social touch constitutes a key component of human social relationships,
although in some conditions with social dysfunction, such as autism, it can be perceived as …

Intranasal oxytocin as a treatment for anxiety and autism: from subclinical to clinical applications

H Yin, M Jiang, T Han, X Xu - Peptides, 2024 - Elsevier
Animal and human studies have demonstrated that intranasal oxytocin (OT) can penetrate
the brain and induce cognitive, emotional, and behavioral changes, particularly in social …

Oro-mucosal administration of oxytocin using medicated lollipops alters social attention, similar to intranasal and lingual routes: Implications for therapeutic use

D Xu, Q Li, Q Zhuang, Y Zhang, S Yao… - Frontiers in …, 2022 - frontiersin.org
A key functional effect of intranasal administration of the neuropeptide oxytocin is on top-
down control of social attention. However, an oro-mucosal administration route may be …

Oral Oxytocin Facilitates Responses to Emotional Faces in Reward and Emotional-Processing Networks in Females

C Lan, Y Chen, Y Zhang, J Kou, L Huang, T Xu… - …, 2023 - karger.com
Introduction: Oxytocin (OXT) is proposed as a potential therapeutic peptide for social
dysfunction due to its modulatory actions on socioemotional regulation in humans. While the …

Oral administration of oxytocin, like intranasal administration, decreases top-down social attention

Q Zhuang, X Zheng, S Yao, W Zhao… - International Journal …, 2022 - academic.oup.com
Background The neuropeptide oxytocin (OXT) modulates social cognition by increasing
attention to social cues and may have therapeutic potential for impaired social attention in …

Effects of arginine vasopressin on human anxiety and associations with sex, dose, and V1a-receptor genotype

RR Thompson, D Price, D Burris, A Cloutier… - …, 2024 - Springer
Objective To test if AVP has dose-dependent effects on anxiety in men and/or women and if
a particular allele within the RS3 promoter region of the V1a receptor gene is associated …

Oromucosal Administration of Oxytocin: The Development of 'Oxipops'

D Xu, C Lan, J Kou, S Yao, W Zhao, KM Kendrick - Pharmaceutics, 2024 - mdpi.com
The role of the hypothalamic neuropeptide oxytocin in influencing the brain and behavior
has been the subject of widespread research over the last few decades due, most notably, to …

The Oxytocin Puzzle: Unlocking Alzheimer's Disease

MC Selles, MM Oliveira - Journal of Alzheimer's Disease, 2024 - content.iospress.com
Alzheimer's disease is a multi-factorial disease that disrupts many aspects of human
behavior. In this comment, we highlight the work by Koulousakis et al. published in a recent …