Background: An ENDO-European Reference Network (ERN) initiative was launched that
was endorsed by the European Society for Pediatric Endocrinology and the European …

Phthalates are ubiquitous environmental contaminants which are used in industry as
plasticizers and additives in cosmetics. They are classified as Endocrine Disrupting …

While neurodevelopmental disorders (NDDs) are highly heritable, several environmental
risk factors have also been suggested. However, the role of familial confounding is unclear …

Congenital hypothyroidism (CH) occurs in approximately 1: 2,000 to 1: 4,000 newborns. The
clinical manifestations are often subtle or not present at birth. This likely is due to trans …

Unrecognized congenital hypothyroidism leads to mental retardation. Newborn screening
and thyroid therapy started within 2 weeks of age can normalize cognitive development. The …

In order to search for sequence variants conferring risk of thyroid cancer we conducted a
genome-wide association study in 192 and 37,196 Icelandic cases and controls …

Through its actions on regulatory genes that form, grow and sculpt the brain, thyroid
hormone (TH) is essential for human brain development. Although much of what we know …

Thyroid hormone has important effects on almost every organ system and plays a crucial
role in normal growth and neurologic development. Congenital hypothyroidism affects …

Background: There is concern over potential neurobehavioral effects of prenatal phthalate
exposures, but available data are inconsistent. Objectives: We examined associations …

Untreated congenital hypothyroidism (CH) leads to intellectual disabilities. Prompt diagnosis
by newborn screening (NBS) leading to early and adequate treatment results in grossly …