Towards network-guided neuromodulation for epilepsy

RJ Piper, RM Richardson, G Worrell, DW Carmichael… - Brain, 2022 - academic.oup.com
Epilepsy is well-recognized as a disorder of brain networks. There is a growing body of
research to identify critical nodes within dynamic epileptic networks with the aim to target …

Adult epilepsy

AA Asadi-Pooya, F Brigo, S Lattanzi, I Blumcke - The Lancet, 2023 - thelancet.com
Epilepsy is a common medical condition that affects people of all ages, races, social classes,
and geographical regions. Diagnosis of epilepsy remains clinical, and ancillary …

Timing of referral to evaluate for epilepsy surgery: Expert Consensus Recommendations from the Surgical Therapies Commission of the International League Against …

L Jehi, N Jette, CS Kwon, CB Josephson… - …, 2022 - Wiley Online Library
Epilepsy surgery is the treatment of choice for patients with drug‐resistant seizures. A timely
evaluation for surgical candidacy can be life‐saving for patients who are identified as …

Drug resistance in epilepsy

E Perucca, P Perucca, HS White, EC Wirrell - The Lancet Neurology, 2023 - thelancet.com
Drug resistance is estimated to affect about a third of individuals with epilepsy, but its
prevalence differs in relation to the epilepsy syndrome, the cause of epilepsy, and other …

Cross-frequency coupling and intelligent neuromodulation

CH Yeh, C Zhang, W Shi, MT Lo… - Cyborg and bionic …, 2023 - spj.science.org
Cross-frequency coupling (CFC) reflects (nonlinear) interactions between signals of different
frequencies. Evidence from both patient and healthy participant studies suggests that CFC …

Neurostimulation in people with drug‐resistant epilepsy: systematic review and meta‐analysis from the ILAE surgical therapies commission

L Touma, B Dansereau, AY Chan, N Jetté, CS Kwon… - …, 2022 - Wiley Online Library
Objective Summarize the current evidence on efficacy and tolerability of vagus nerve
stimulation (VNS), responsive neurostimulation (RNS), and deep brain stimulation (DBS) …

Transcutaneous vagus nerve stimulation-a brief introduction and overview

MJ Hilz - Autonomic Neuroscience, 2022 - Elsevier
Invasive cervical vagus nerve stimulation (VNS) is approved for the treatment of epilepsies,
depression, obesity, and for stroke-rehabilitation. The procedure requires surgery, has side …

Therapeutic strategies to ameliorate neuronal damage in epilepsy by regulating oxidative stress, mitochondrial dysfunction, and neuroinflammation

S Madireddy, S Madireddy - Brain sciences, 2023 - mdpi.com
Epilepsy is a central nervous system disorder involving spontaneous and recurring seizures
that affects 50 million individuals globally. Because approximately one-third of patients with …

Mapping lesion-related epilepsy to a human brain network

FL Schaper, J Nordberg, AL Cohen, C Lin, J Hsu… - JAMA …, 2023 - jamanetwork.com
Importance It remains unclear why lesions in some locations cause epilepsy while others do
not. Identifying the brain regions or networks associated with epilepsy by mapping these …

[HTML][HTML] Epileptic-network-based prediction and control of seizures in humans

K Lehnertz, T Bröhl, R von Wrede - Neurobiology of Disease, 2023 - Elsevier
Epilepsy is now conceptualized as a network disease. The epileptic brain network
comprises structurally and functionally connected cortical and subcortical brain regions …