ImmunoPET: antibody-based PET imaging in solid tumors

R Manafi-Farid, B Ataeinia, S Ranjbar… - Frontiers in …, 2022 - frontiersin.org
Immuno-positron emission tomography (immunoPET) is a molecular imaging modality
combining the high sensitivity of PET with the specific targeting ability of monoclonal …

ImmunoPET targeting receptor tyrosine kinase: clinical applications

F Linguanti, EM Abenavoli, R Calabretta, V Berti… - Cancers, 2023 - mdpi.com
Simple Summary Receptor tyrosine kinases (RTKs) are a family of transmembrane proteins
that play crucial roles in regulating various cellular processes. The introduction of …

[89Zr]-Atezolizumab-PET Imaging Reveals Longitudinal Alterations in PDL1 during Therapy in TNBC Preclinical Models

AVF Massicano, PN Song, A Mansur, SL White… - Cancers, 2023 - mdpi.com
Simple Summary Triple-negative breast cancer is characterized by a lack of targetable
treatment receptors and current standard of care options, such as radiation therapy and …

Advances in nuclear medicine-based molecular imaging in head and neck squamous cell carcinoma

D Li, X Li, J Zhao, F Tan - Journal of Translational Medicine, 2022 - Springer
Head and neck squamous cell carcinomas (HNSCCs) are often aggressive, making
advanced disease very difficult to treat using contemporary modalities, such as surgery …

Novel receptor tyrosine kinase pathway inhibitors for targeted radionuclide therapy of glioblastoma

J Bolcaen, S Nair, CHS Driver, TMG Boshomane… - Pharmaceuticals, 2021 - mdpi.com
Glioblastoma (GB) remains the most fatal brain tumor characterized by a high infiltration rate
and treatment resistance. Overexpression and/or mutation of receptor tyrosine kinases is …

89Zr-panitumumab PET imaging for preoperative assessment of ameloblastoma in a PDX model

LD Stone, AVF Massicano, TM Stevens, JM Warram… - Scientific Reports, 2022 - nature.com
Accurate assessment of tumor margins with specific, non-invasive imaging would result in
the preservation of healthy tissue and improve long-term local tumor control, thereby …

Radiopharmaceuticals developed for 89Zr-Immuno-PET

B Altıparmak Güleç, F Yurt - Journal of Radioanalytical and Nuclear …, 2021 - Springer
The development of molecular imaging agents used for imaging of cancer tissue is of great
importance for the early detection of cancer. Positron emission tomography (PET) …

Preparation, quality control, and absorbed dose estimation of 89Zr-DFO-Cetuximab for imaging of EGFR-expressing tumors

S Zolghadri, F Mohammadpour-Ghazi… - … of Radioanalytical and …, 2024 - Springer
In this study, 89 Zr-DFO-Cetuximab was prepared under the optimized conditions with a
radiochemical purity> 99%, and a specific activity of 185 GBq g− 1. Cellular studies on …

Immune-directed molecular imaging biomarkers

N Pandit-Taskar, MA Postow - Seminars in Nuclear Medicine, 2020 - Elsevier
Imaging has played a critical role in the management of patients with cancer. Novel
therapies are emerging rapidly; however, they are effective only in some patients. With the …

Use of Imaging in Radiotherapy for Head and Neck Cancer

S Nuyts, S Deschuymer - Head and Neck Cancer Imaging, 2021 - Springer
Wider availability of and technical improvements in anatomic and biological imaging have
facilitated the implementation of high-precision three-dimensional conformal and intensity …