Estimating individual treatment effects on COPD exacerbations by causal machine learning on randomised controlled trials

K Verstraete, I Gyselinck, H Huts, N Das, M Topalovic… - thorax, 2023 - thorax.bmj.com
Rationale Estimating the causal effect of an intervention at individual level, also called
individual treatment effect (ITE), may help in identifying response prior to the intervention …

Effects of cigarette smoke exposure on pulmonary physiology, muscle strength and exercise capacity in a retrospective cohort with 30,000 subjects

A Adatia, M Wahab, I Shahid, A Moinuddin, KJ Killian… - PLoS …, 2021 - journals.plos.org
Background The effects of long-term cigarette smoke exposure on pulmonary physiology
and how those effects lead to reduced exercise capacity are not well established. Methods …

Association of platelet count with all-cause mortality and risk of cardiovascular and respiratory morbidity in stable COPD

A Fawzy, JA Anderson, NJ Cowans, C Crim, R Wise… - Respiratory …, 2019 - Springer
Background Platelet count is a prognostic indicator in the general population and elderly.
Thrombocytosis during acute exacerbation of COPD (AECOPD) has been associated with …

Long-term use of inhaled glucocorticoids in patients with stable chronic obstructive pulmonary disease and risk of bone fractures: a narrative review of the literature

G Caramori, P Ruggeri, F Arpinelli, L Salvi… - International journal of …, 2019 - Taylor & Francis
Patients with chronic obstructive pulmonary disease (COPD) demonstrate a greater
osteoporosis prevalence than the general population. This osteoporosis risk may be …

Coexisting chronic obstructive pulmonary disease and cardiovascular disease in clinical practice: a diagnostic and therapeutic challenge

P Leong, MI Macdonald, BS Ko… - Medical Journal of …, 2019 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD)
frequently coexist but combined disease is often not recognised. Since symptoms overlap …

Cigarette smoking and response to inhaled corticosteroids in COPD

SP Bhatt, JA Anderson, RD Brook… - European …, 2018 - Eur Respiratory Soc
Cigarette smoking and response to inhaled corticosteroids in COPD | European Respiratory
Society Skip to main content Main menu Home Current issue ERJ Early View Past issues ERS …

Risk of adverse reactions associated with inhaled corticosteroids for chronic obstructive pulmonary disease: A meta-analysis

C Lu, X Mao - Medicine, 2024 - journals.lww.com
Background: In the majority of current therapeutic regimens for chronic obstructive
pulmonary disease (COPD), bronchodilators are coupled with inhaled corticosteroids (ICS) …

Evidence-based management approaches for patients with severe chronic obstructive pulmonary disease (COPD): A practice review

Y Fu, EJ Chapman, AC Boland… - Palliative …, 2022 - journals.sagepub.com
Background: Patients with chronic obstructive pulmonary disease (COPD) face limited
treatment options and inadequate access to palliative care. Aim: To provide a pragmatic …

Challenging the obesity paradox: extreme obesity and COPD mortality in the SUMMIT trial

EP Brigham, JA Anderson, RD Brook… - ERJ Open …, 2021 - Eur Respiratory Soc
Populations with COPD demonstrate higher survival in overweight and obese compared
with normal weight; the “obesity paradox”. Relationships in less-severe COPD are unclear …

Stroke risk among patients with chronic obstructive pulmonary disease: A systematic review and meta-analysis

YR Kim, IC Hwang, YJ Lee, EB Ham, DK Park, S Kim - Clinics, 2018 - SciELO Brasil
Increased stroke risk among chronic obstructive pulmonary disease patients has not yet
been established. In this study, we conducted a systematic review and meta-analysis to …