Biological responses to physicochemical properties of biomaterial surface
Biomedical scientists use chemistry-driven processes found in nature as an inspiration to
design biomaterials as promising diagnostic tools, therapeutic solutions, or tissue …
design biomaterials as promising diagnostic tools, therapeutic solutions, or tissue …
Cellular mechanotransduction: from tension to function
F Martino, AR Perestrelo, V Vinarský, S Pagliari… - Frontiers in …, 2018 - frontiersin.org
Living cells are constantly exposed to mechanical stimuli arising from the surrounding
extracellular matrix (ECM) or from neighboring cells. The intracellular molecular processes …
extracellular matrix (ECM) or from neighboring cells. The intracellular molecular processes …
Nanoparticles in tissue engineering: applications, challenges and prospects
Tissue engineering (TE) is an interdisciplinary field integrating engineering, material science
and medical biology that aims to develop biological substitutes to repair, replace, retain, or …
and medical biology that aims to develop biological substitutes to repair, replace, retain, or …
Bone physiology as inspiration for tissue regenerative therapies
D Lopes, C Martins-Cruz, MB Oliveira, JF Mano - Biomaterials, 2018 - Elsevier
The development, maintenance of healthy bone and regeneration of injured tissue in the
human body comprise a set of intricate and finely coordinated processes. However, an …
human body comprise a set of intricate and finely coordinated processes. However, an …
High‐aspect‐ratio nanostructured surfaces as biological metamaterials
SG Higgins, M Becce… - Advanced …, 2020 - Wiley Online Library
Materials patterned with high‐aspect‐ratio nanostructures have features on similar length
scales to cellular components. These surfaces are an extreme topography on the cellular …
scales to cellular components. These surfaces are an extreme topography on the cellular …
Materials as stem cell regulators
The stem cell/material interface is a complex, dynamic microenvironment in which the cell
and the material cooperatively dictate one another's fate: the cell by remodelling its …
and the material cooperatively dictate one another's fate: the cell by remodelling its …
Magnetic nanostructures: Rational design and fabrication strategies toward diverse applications
In recent years, the continuous development of magnetic nanostructures (MNSs) has
tremendously promoted both fundamental scientific research and technological applications …
tremendously promoted both fundamental scientific research and technological applications …
Surface roughness gradients reveal topography‐specific mechanosensitive responses in human mesenchymal stem cells
Y Hou, W Xie, L Yu, LC Camacho, C Nie, M Zhang… - Small, 2020 - Wiley Online Library
The topographic features of an implant, which mechanically regulate cell behaviors and
functions, are critical for the clinical success in tissue regeneration. How cells sense and …
functions, are critical for the clinical success in tissue regeneration. How cells sense and …
Surface roughness and substrate stiffness synergize to drive cellular mechanoresponse
Material surface topographic features have been shown to be crucial for tissue regeneration
and surface treatment of implanted devices. Many biomaterials were investigated with …
and surface treatment of implanted devices. Many biomaterials were investigated with …
From nano to micro: topographical scale and its impact on cell adhesion, morphology and contact guidance
Topography, among other physical factors such as substrate stiffness and extracellular
forces, is known to have a great influence on cell behaviours. Optimization of topographical …
forces, is known to have a great influence on cell behaviours. Optimization of topographical …