Biological responses to physicochemical properties of biomaterial surface

M Rahmati, EA Silva, JE Reseland… - Chemical Society …, 2020 - pubs.rsc.org
Biomedical scientists use chemistry-driven processes found in nature as an inspiration to
design biomaterials as promising diagnostic tools, therapeutic solutions, or tissue …

Cellular mechanotransduction: from tension to function

F Martino, AR Perestrelo, V Vinarský, S Pagliari… - Frontiers in …, 2018 - frontiersin.org
Living cells are constantly exposed to mechanical stimuli arising from the surrounding
extracellular matrix (ECM) or from neighboring cells. The intracellular molecular processes …

Nanoparticles in tissue engineering: applications, challenges and prospects

A Hasan, M Morshed, A Memic, S Hassan… - International journal …, 2018 - Taylor & Francis
Tissue engineering (TE) is an interdisciplinary field integrating engineering, material science
and medical biology that aims to develop biological substitutes to repair, replace, retain, or …

Bone physiology as inspiration for tissue regenerative therapies

D Lopes, C Martins-Cruz, MB Oliveira, JF Mano - Biomaterials, 2018 - Elsevier
The development, maintenance of healthy bone and regeneration of injured tissue in the
human body comprise a set of intricate and finely coordinated processes. However, an …

High‐aspect‐ratio nanostructured surfaces as biological metamaterials

SG Higgins, M Becce… - Advanced …, 2020 - Wiley Online Library
Materials patterned with high‐aspect‐ratio nanostructures have features on similar length
scales to cellular components. These surfaces are an extreme topography on the cellular …

Materials as stem cell regulators

WL Murphy, TC McDevitt, AJ Engler - Nature materials, 2014 - nature.com
The stem cell/material interface is a complex, dynamic microenvironment in which the cell
and the material cooperatively dictate one another's fate: the cell by remodelling its …

Magnetic nanostructures: Rational design and fabrication strategies toward diverse applications

S Wang, J Xu, W Li, S Sun, S Gao, Y Hou - Chemical reviews, 2022 - ACS Publications
In recent years, the continuous development of magnetic nanostructures (MNSs) has
tremendously promoted both fundamental scientific research and technological applications …

Surface roughness gradients reveal topography‐specific mechanosensitive responses in human mesenchymal stem cells

Y Hou, W Xie, L Yu, LC Camacho, C Nie, M Zhang… - Small, 2020 - Wiley Online Library
The topographic features of an implant, which mechanically regulate cell behaviors and
functions, are critical for the clinical success in tissue regeneration. How cells sense and …

Surface roughness and substrate stiffness synergize to drive cellular mechanoresponse

Y Hou, L Yu, W Xie, LC Camacho, M Zhang, Z Chu… - Nano …, 2019 - ACS Publications
Material surface topographic features have been shown to be crucial for tissue regeneration
and surface treatment of implanted devices. Many biomaterials were investigated with …

From nano to micro: topographical scale and its impact on cell adhesion, morphology and contact guidance

AT Nguyen, SR Sathe, EKF Yim - Journal of Physics: Condensed …, 2016 - iopscience.iop.org
Topography, among other physical factors such as substrate stiffness and extracellular
forces, is known to have a great influence on cell behaviours. Optimization of topographical …