Natural products have been extensively applied in clinical practice, characterized by multi-
component and multi-target, many pharmacodynamic substances, complex action …

Flavonoids are natural phytochemicals that have therapeutic effects and act in the
prevention of several pathologies. These phytochemicals can be found in seeds, grains, tea …

Citrus (genus Citrus L.) fruits are essential sources of bioactive compounds with antioxidant
properties, such as flavonoids. These polyphenolic compounds are divided into subclasses …

Abstract Neohesperidin (hesperetin 7-O-neohesperidoside), a well-known flavanone
glycoside widely found in citrus fruits, exhibits a variety of biological activities, with potential …

Neohesperidin dihydrochalcone is an artificial sweetener with remarkable antioxidant
activity, stable to basic or acidic conditions and elevated temperatures. This bioactive …

High-fat diet (HFD) is closely related to the formation of metabolic diseases. Studies have
confirmed that neohesperidin dihydrochalcone (NHDC) possesses the biological activity of …

Scope Mild cognitive impairment is associated with a high prevalence of dementia. The
study examines the benefits of a modified Korean MIND (K‐MIND) diet and explores …

Links between bronchial asthma and depression have recently become a great subject of
interest. The present study was carried out to assess the protective role of hesperidin against …

Worldwide, the demand for natural and synthetic sweeteners in the food industry as an
alternative to refined sugar is increasing. This has prompted more research to be conducted …

Dysregulation of cathepsin S (Cat S), a cysteine protease involved in extracellular-matrix
and basement membrane (BM) degradation, is a concomitant feature of several …