[HTML][HTML] The hidden power of secondary metabolites in plant-fungi interactions and sustainable phytoremediation

NA Elhamouly, OA Hewedy, A Zaitoon… - Frontiers in Plant …, 2022 - frontiersin.org
The global environment is dominated by various small exotic substances, known as
secondary metabolites, produced by plants and microorganisms. Plants and fungi are …

Inflammasome-mediated GSDMD activation facilitates escape of Candida albicans from macrophages

X Ding, H Kambara, R Guo, A Kanneganti… - Nature …, 2021 - nature.com
Candida albicans is the most common cause of fungal sepsis. Inhibition of inflammasome
activity confers resistance to polymicrobial and LPS-induced sepsis; however …

PADs and NETs in digestive system: from physiology to pathology

YH Song, ZJ Wang, L Kang, ZX He, SB Zhao… - Frontiers in …, 2023 - frontiersin.org
Peptidylarginine deiminases (PADs) are the only enzyme class known to deiminate arginine
residues into citrulline in proteins, a process known as citrullination. This is an important post …

Candidalysin triggers epithelial cellular stresses that induce necrotic death

M Blagojevic, G Camilli, M Maxson, B Hube… - Cellular …, 2021 - Wiley Online Library
Candida albicans is a common opportunistic fungal pathogen that causes a wide range of
infections from superficial mucosal to hematogenously disseminated candidiasis. The …

[HTML][HTML] Anisomycin has a potential toxicity of promoting cuproptosis in human ovarian cancer stem cells by attenuating YY1/lipoic acid pathway activation

X Nie, H Chen, Y Xiong, J Chen, T Liu - Journal of Cancer, 2022 - ncbi.nlm.nih.gov
Ovarian cancer is a highly malignant gynecologic tumor that seriously endangers women's
health. We previously demonstrated that anisomycin significantly inhibited the activity of …

Mangiferin mitigates lipopolysaccharide-induced lung injury by inhibiting NLRP3 inflammasome activation

N Li, R Xiong, R He, B Liu, B Wang… - Journal of Inflammation …, 2021 - Taylor & Francis
Scope Mangiferin (MF) is a natural phytopolyphenol, which displays potential
pharmacological properties involving antibacterial, anti-inflammation, antioxidant and anti …

Processing and biomedical applications of novel eco-sustainable fluconazole–loaded zinc oxide (ZnO) encapsulated chitosan (CS) biopolymer nanocomposite by …

A Das, T Ringu, S Ghosh, N Pramanik - Materials Today Communications, 2023 - Elsevier
Drug resistance and a lack of effective antifungal treatments have spurred the research and
development of novel therapeutics to combat the fungus Candida albicans. Candida is …

[HTML][HTML] Extracellular vesicles derived from Talaromyces marneffei contain immunogenic compounds and modulate THP-1 macrophage responses

K Pruksaphon, A Amsri, P Thammasit… - Frontiers in …, 2023 - frontiersin.org
Pathogenic eukaryotes including fungi release extracellular vesicles (EVs) which are
composed of a variety of bioactive components, including peptides, nucleic acids …

[HTML][HTML] Insights into DNMT1 and programmed cell death in diseases

L Yan, Q Geng, Z Cao, B Liu, L Li, P Lu, L Lin… - Biomedicine & …, 2023 - Elsevier
Abstract DNMT1 (DNA methyltransferase 1) is the predominant member of the DNMT family
and the most abundant DNMT in various cell types. It functions as a maintenance DNMT and …

[HTML][HTML] Poly (I: C), a double stranded RNA analog, activates the anti-viral DNA sensors in buffalo fibroblasts

JS Chera, S Kumar, AK Bairagi, A Kumar, P Chandra… - Veterinary Vaccine, 2023 - Elsevier
Polyinosinic: polycytidylic acid or poly (I: C) is a double stranded RNA analog that is known
for stimulating RNA sensing pathways in a variety of cell culture and animal models …