The ability to adaptively regulate emotion is essential for mental and physical well-being.
How should we organize the myriad ways people attempt to regulate their emotions? We …

Reversal learning paradigms are among the most widely used tests of cognitive flexibility
and have been used as assays, across species, for altered cognitive processes in a host of …

The positive-negative axis of emotional valence has long been recognized as fundamental
to adaptive behavior, but its origin and underlying function have largely eluded formal …

To better understand the reward circuitry in human brain, we conducted activation likelihood
estimation (ALE) and parametric voxel-based meta-analyses (PVM) on 142 neuroimaging …

Abstract Changes in response contingencies require adjusting ones assumptions about
outcomes of behaviors. Such adaptation processes are driven by reward prediction error …

Attention-deficit/hyperactivity disorder (ADHD) and conduct disorder overlap behaviorally,
clinically, and cognitively. An important question of potential future clinical relevance is …

Cognitive functions dependent on the prefrontal cortex, such as the ability to suppress
behavior (response inhibition) and to learn from complex feedback (probabilistic learning) …

The authors explore the division of labor between the basal ganglia-dopamine (BG-DA)
system and the orbitofrontal cortex (OFC) in decision making. They show that a primitive …

Context The orbitofrontal cortex (OFC)–striatal circuit, which is important for motivational
behavior, is assumed to be involved in the pathophysiology of obsessive-compulsive …

Different subregions of the prefrontal cortex (PFC) contribute to the ability to respond flexibly
to changes in reward contingencies, with the medial versus orbitofrontal cortex (OFC) …