Sarcopenia and cardiovascular diseases: a systematic review and meta‐analysis

X Zuo, X Li, K Tang, R Zhao, M Wu… - Journal of Cachexia …, 2023 - Wiley Online Library
Sarcopenia is an age‐related disease and is often accompanied by other diseases. Now,
many studies have shown that cardiovascular diseases (CVDs) may raise the incidence rate …

[HTML][HTML] Beyond cardiomyocytes: cellular diversity in the heart's response to exercise

LE Trager, M Lyons, A Kuznetsov, C Sheffield… - Journal of Sport and …, 2023 - Elsevier
Abstract Cardiomyocytes comprise∼ 70% to 85% of the total volume of the adult
mammalian heart but only about 25% to 35% of its total number of cells. Advances in single …

HIPK1 Inhibition Protects against Pathological Cardiac Hypertrophy by Inhibiting the CREB‐C/EBPβ Axis

Y Bei, Y Zhu, M Wei, M Yin, L Li, C Chen… - Advanced …, 2023 - Wiley Online Library
Inhibition of pathological cardiac hypertrophy is recognized as an important therapeutic
strategy for heart failure, although effective targets are still lacking in clinical practice …

Exercise mitigates flow recirculation and activates metabolic transducer SCD1 to catalyze vascular protective metabolites

S Cavallero, M Roustaei, S Satta, JM Cho, H Phan… - Science …, 2024 - science.org
Exercise promotes pulsatile shear stress in the arterial circulation and ameliorates
cardiometabolic diseases. However, exercise-mediated metabolic transducers for vascular …

[HTML][HTML] Exosomal non-coding RNA mediates macrophage polarization: roles in cardiovascular diseases

H Wang, X Ye, M Spanos, H Wang, Z Yang, G Li, J Xiao… - Biology, 2023 - mdpi.com
Simple Summary The role of exosomal non-coding RNA (ncRNA) in regulating macrophage
polarization and the role of polarized macrophages as an important source of extracellular …

Advances in metabolic remodeling and intervention strategies in heart failure

S Meng, Y Yu, S Yu, S Zhu, M Shi, M Xiang… - Journal of Cardiovascular …, 2024 - Springer
The heart is the most energy-demanding organ throughout the whole body. Perturbations or
failure in energy metabolism contributes to heart failure (HF), which represents the …

Moderate‐Intensity Exercise Maintains Redox Homeostasis for Cardiovascular Health

J Jiang, L Ni, X Zhang, P Gokulnath… - Advanced …, 2023 - Wiley Online Library
It is well known that exercise is beneficial for cardiovascular health. Oxidative stress is the
common pathological basis of many cardiovascular diseases. The overproduction of free …

[HTML][HTML] The metabolic fingerprint of doxorubicin-induced cardiotoxicity in male CD-1 mice fades away with time while autophagy increases

SR Brandão, A Reis-Mendes, MJ Neuparth… - Pharmaceuticals, 2023 - mdpi.com
The cardiotoxicity of doxorubicin (DOX) may manifest at the beginning/during treatment or
years after, compromising patients' quality of life. We intended to study the cardiac pathways …

[HTML][HTML] Shaping the future of cardiac wellness: exploring revolutionary approaches in disease management and prevention

TA Addissouky, IET El Sayed, MMA Ali… - Journal of Clinical …, 2024 - scientificarchives.com
Cardiovascular diseases (CVDs) remain a leading cause of morbidity and mortality
worldwide. Effective prevention and management strategies are essential to reduce the …

Resistance training up-regulates Smyd1 expression and inhibits oxidative stress and endoplasmic reticulum stress in the heart of middle-aged mice

J Tang, C Wu, Y Xu, B Yang, Y Xi, M Cai… - Free Radical Biology and …, 2024 - Elsevier
Persistent oxidative stress and endoplasmic reticulum (ER) stress are the primary
mechanisms of age-related cardiovascular diseases. Although exercise training is viewed …