Sarcopenia and cardiovascular diseases: a systematic review and meta‐analysis

X Zuo, X Li, K Tang, R Zhao, M Wu… - Journal of Cachexia …, 2023 - Wiley Online Library
Sarcopenia is an age‐related disease and is often accompanied by other diseases. Now,
many studies have shown that cardiovascular diseases (CVDs) may raise the incidence rate …

Shaping the future of cardiac wellness: exploring revolutionary approaches in disease management and prevention

TA Addissouky, IET El Sayed, MMA Ali… - Journal of Clinical …, 2024 - scientificarchives.com
Cardiovascular diseases (CVDs) remain a leading cause of morbidity and mortality
worldwide. Effective prevention and management strategies are essential to reduce the …

Exercise-induced miR-210 promotes cardiomyocyte proliferation and survival and mediates exercise-induced cardiac protection against ischemia/reperfusion injury

Y Bei, H Wang, Y Liu, Z Su, X Li, Y Zhu, Z Zhang, M Yin… - Research, 2024 - spj.science.org
Exercise can stimulate physiological cardiac growth and provide cardioprotection effect in
ischemia/reperfusion (I/R) injury. MiR-210 is regulated in the adaptation process induced by …

[HTML][HTML] Beyond cardiomyocytes: cellular diversity in the heart's response to exercise

LE Trager, M Lyons, A Kuznetsov, C Sheffield… - Journal of Sport and …, 2023 - Elsevier
Abstract Cardiomyocytes comprise∼ 70% to 85% of the total volume of the adult
mammalian heart but only about 25% to 35% of its total number of cells. Advances in single …

HIPK1 Inhibition Protects against Pathological Cardiac Hypertrophy by Inhibiting the CREB‐C/EBPβ Axis

Y Bei, Y Zhu, M Wei, M Yin, L Li, C Chen… - Advanced …, 2023 - Wiley Online Library
Inhibition of pathological cardiac hypertrophy is recognized as an important therapeutic
strategy for heart failure, although effective targets are still lacking in clinical practice …

Cardiovascular effects of weight loss in old adults with overweight/obesity according to change in skeletal muscle mass

X Cai, M Liu, X Xu, S Zhang, R Huang… - Journal of Cachexia …, 2024 - Wiley Online Library
Background Patients with overweight/obesity and type 2 diabetes are encouraged to lose
weight, but not all losing weight gain better cardiovascular health, especially old adults. The …

The metabolic fingerprint of doxorubicin-induced cardiotoxicity in male CD-1 mice fades away with time while autophagy increases

SR Brandão, A Reis-Mendes, MJ Neuparth… - Pharmaceuticals, 2023 - mdpi.com
The cardiotoxicity of doxorubicin (DOX) may manifest at the beginning/during treatment or
years after, compromising patients' quality of life. We intended to study the cardiac pathways …

Exercise mitigates flow recirculation and activates metabolic transducer SCD1 to catalyze vascular protective metabolites

S Cavallero, M Roustaei, S Satta, JM Cho, H Phan… - Science …, 2024 - science.org
Exercise promotes pulsatile shear stress in the arterial circulation and ameliorates
cardiometabolic diseases. However, exercise-mediated metabolic transducers for vascular …

Octopamine Rescues Endurance and Climbing Speed in Drosophila Clkout Mutants with Circadian Rhythm Disruption

M Safdar, RJ Wessells - Cells, 2023 - mdpi.com
Circadian rhythm disturbances are associated with various negative health outcomes,
including an increasing incidence of chronic diseases with high societal costs. While …

Molecular insights of exercise therapy in disease prevention and treatment

D Walzik, TY Wences Chirino, P Zimmer… - Signal Transduction and …, 2024 - nature.com
Despite substantial evidence emphasizing the pleiotropic benefits of exercise for the
prevention and treatment of various diseases, the underlying biological mechanisms have …