In Vitro and In Vivo Chaperone Effect of (R)-2-amino-6-(1R, 2S)-1, 2-dihydroxypropyl)-5, 6, 7, 8-tetrahydropterin-4 (3H)-one on the C1473G Mutant Tryptophan …
AB Arefieva, PD Komleva, VS Naumenko, NV Khotskin… - Biomolecules, 2023 - mdpi.com
Tryptophan hydroxylase 2 (TPH2) is the key and rate-limiting enzyme of serotonin (5-HT)
synthesis in the mammalian brain. The 1473G mutation in the Tph2 gene decreases TPH2 …
synthesis in the mammalian brain. The 1473G mutation in the Tph2 gene decreases TPH2 …
Interaction Between a High-Fat Diet and Tau Pathology in Mice: Implications for Alzheimer's Disease
YJ Jang, MG Choi, BJ Yoo, KJ Lee… - Journal of …, 2024 - content.iospress.com
Background: Obesity is a modifiable risk factor for Alzheimer's disease (AD). However, its
relation with tau pathology (ie, aberrant tau protein behavior in tauopathies such as AD) has …
relation with tau pathology (ie, aberrant tau protein behavior in tauopathies such as AD) has …
[引用][C] Tetrahydrobiopterin shifts the balance from oxidative stress to NO signalling in Duchenne muscular dystrophy
RD Wuebbles, A Oliveira‐Santos… - Acta Physiologica, 2021 - Wiley Online Library
In this issue, Lindsay et al, 2021 investigated if patients with Duchenne muscular dystrophy
(DMD) had reduced levels of the antioxidant and arginine-NO coupling cofactor …
(DMD) had reduced levels of the antioxidant and arginine-NO coupling cofactor …