At the centenary of D'Arcy Thompson's seminal work 'On Growth and Form', pioneering the
description of principles of morphological changes during development and evolution …

The assumption that during cortical embryogenesis neurons and synaptic connections are
selected to form an ensemble maximising synchronous oscillation explains mesoscopic …

Brain network connections rewire adaptively in response to neural activity. Adaptive rewiring
may be understood as a process which, at its every step, is aimed at optimizing the efficiency …

During brain development, billions of axons must navigate over multiple spatial scales to
reach specific neuronal targets, and so build the processing circuits that generate the …

Current research in the field of computational biology often involves simulations on high-
performance computer clusters. It is crucial that the code of such simulations is efficient and …

Axonal morphology displays large variability and complexity, yet the canonical regularities of
the cortex suggest that such wiring is based on the repeated initiation of a small set of …

Many real-world networks contain highly connected nodes called hubs. Hubs are often
crucial for network function and spreading dynamics. However, classical models of how …

Individual retinal cell types exhibit semi-regular spatial patterns called retinal mosaics.
Retinal ganglion cells (RGCs) and starburst amacrine cells (SACs) are known to exhibit …

Computer simulations have become a very powerful tool for scientific research. In order to
facilitate research in computational biology, the BioDynaMo project aims at a general …

This paper addresses a fundamental line of research in neuroscience: the identification of a
putative neural processing core of the cerebral cortex, often claimed to be “canonical”. This …