Pyrroloquinoline-quinone is more than an antioxidant: a vitamin-like accessory factor important in health and disease prevention

KR Jonscher, W Chowanadisai, RB Rucker - Biomolecules, 2021 - mdpi.com
Pyrroloquinoline quinone (PQQ) is associated with biological processes such as
mitochondriogenesis, reproduction, growth, and aging. In addition, PQQ attenuates clinically …

Role of postbiotics in diet-induced metabolic disorders

M Park, M Joung, JH Park, SK Ha, HY Park - Nutrients, 2022 - mdpi.com
Although the prevalence of metabolic disorders has progressively increased over the past
few decades, metabolic disorders can only be effectively treated with calorie restriction and …

Recent advances in the treatment of insulin resistance targeting molecular and metabolic pathways: fighting a losing battle?

M Wolosowicz, S Prokopiuk, TW Kaminski - Medicina, 2022 - mdpi.com
Diabetes Mellitus (DM) is amongst the most notable causes of years of life lost worldwide
and its prevalence increases perpetually. The disease is characterized as multisystemic …

New insights into the diurnal rhythmicity of gut microbiota and its crosstalk with host circadian rhythm

H Wang, H Zhang, Y Su - Animals, 2022 - mdpi.com
Simple Summary There is a growing consensus that the gut microbiota exhibits diurnal
oscillation. The rhythmicity of gut microbiota has fundamental implications for host …

Di-(2-ethylhexyl) phthalate increases plasma glucose and induces lipid metabolic disorders via FoxO1 in adult mice

X Wei, D Yang, B Zhang, X Fan, H Du, R Zhu… - Science of The Total …, 2022 - Elsevier
Abstract Di-(2-ethylhexyl) phthalate (DEHP), an endocrine-disrupting chemical (EDC)
commonly used as a plasticizer, is responsible for widespread environmental pollution …

Obesity modulates the gut microbiome in triple-negative breast cancer

F Hossain, S Majumder, J David, BA Bunnell, L Miele - Nutrients, 2021 - mdpi.com
Triple-negative breast cancer (TNBC) is an aggressive, molecularly heterogeneous subtype
of breast cancer. Obesity is associated with increased incidence and worse prognosis in …

Regulation of liver glucose and lipid metabolism by transcriptional factors and coactivators

B Ramatchandirin, A Pearah, L He - Life, 2023 - mdpi.com
The prevalence of nonalcoholic fatty liver disease (NAFLD) worldwide is on the rise and
NAFLD is becoming the most common cause of chronic liver disease. In the USA, NAFLD …

Preventive effects of polysaccharides from Physalis alkekengi L. on dietary advanced glycation end product-induced insulin resistance in mice associated with the …

Y Wu, L Dong, Y Song, Y Wu, Y Zhang… - International journal of …, 2022 - Elsevier
Advanced glycation end products (AGEs) are commonly found in thermally processed foods,
and long-term high AGE feeding has been reported to have negative effects on body health …

Gut microbiota and childhood malnutrition: Understanding the link and exploring therapeutic interventions

S Zoghi, F Sadeghpour Heravi… - Engineering in Life …, 2024 - Wiley Online Library
Childhood malnutrition is a metabolic condition that affects the physical and mental well‐
being of children and leads to resultant disorders in maturity. The development of childhood …

Co-toxicity of endotoxin and indoxyl sulfate, gut-derived bacterial metabolites, to vascular endothelial cells in coronary arterial disease accompanied by gut dysbiosis

M Choroszy, B Sobieszczańska, K Litwinowicz… - Nutrients, 2022 - mdpi.com
Gut dysbiosis, alongside a high-fat diet and cigarette smoking, is considered one of the
factors promoting coronary arterial disease (CAD) development. The present study aimed to …