Background Cardiotoxicity remains one of the most reported adverse drug reactions that
lead to drug attrition during pre-clinical and clinical drug development. Drug-induced …

A sensitive and simple microextraction approach was developed and validated to
simultaneously determine three antiarrhythmic drugs, propranolol, diltiazem, and verapamil …

Antiarrhythmic and antihypertensive drugs are frequently encountered in post mortem
analysis, and the question may arise as to whether they were administered in therapeutic …

A number of medical conditions are identified as risk factors for suicide death; in particular,
cardiovascular illnesses are recognized as a major suicide risk factor. In this case, self …

Amlodipine is a dihydropyridine calcium channel blocker widely used in the treatment of
high blood pressure and coronary heart disease. Intoxication can lead to reflex tachycardia …

Introduction. Verapamil is a widely used cardiac drug. It belongs to the non-dihydropiridine
subgroup of calcium channel blockers (CCBs), and is used mainly for the treatment of atrial …

Background: Pharmacobezoars are specific types of bezoars formed when medicines, such
as tablets, suspensions, and/or drug delivery systems, aggregate and may cause death by …

Pharmacobezoars develop after an acute overdose or during routine drug administration.
Here, the authors present a case of fatal multidrug overdose involving a 62-year-old woman …

Introduction. Verapamil is a widely used cardiac drug. It belongs to the non-dihydropiridine
subgroup of calcium channel blockers (CCBs), and is used mainly for the treatment of atrial …

Résumé Depuis 2019, le laboratoire de toxicologie du CHU de Lille met en œuvre en 24/24
un criblage toxicologique par spectrométrie de masse haute résolution (CL-SMHR). Nous …