Multidrug-resistant, Gram-negative infection is a major global determinant of morbidity,
mortality and cost of care. The advent of nanomedicine has enabled tailored engineering of …

Extracellular zinc-containing metalloproteases are widely distributed in the bacterial world.
The most extensively studied are those which are associated with pathogenic bacteria or …

The metalloprotease gene (vppC) from Vibrio parahaemolyticus 04 has been cloned and
sequenced. The vppC gene contains an open reading frame of 2442 nucleotides encoding …

An exocellular metalloprotease produced by Vibrio fluvialis, an enteropathogenic vibrio, was
purified and characterized. The metalloprotease (V. fluvialis protease [VFP]) was found to …

Aeromonas sobria causes septic shock, a condition associated with high mortality. To study
the mechanism of septic shock by A. sobria infection, we examined the vascular leakage …

Vibrio mimicus is a typical strain of Vibrio cholerae and produces a phospholipase (PhlA)
which shares a highly conserved amino acid sequence with the lecithinase (Lec) of V …

We have shown previously that the C-terminal region of the extracellular metalloprotease of
Vibrio mimicus (VMC) is essential for collagenase activity. Here, we demonstrate that …

To investigate the enzymatic properties of Vibrio mimicus metalloprotease, the mature
metalloprotease gene (vmc) was overexpressed in Escherichia coli and the recombinant …

An alkaliphilic protease-producing bacterium was isolated and identified as Vibrio fluvialis
TKU005. Two surfactant-stable alkaline metalloproteases (FI and FII) were purified from the …

The structural gene prtVp encoding the extracellular protease of Vibrio parahaemolyticus
strain 93 was cloned in Escherichia coli and sequenced. The cloned DNA fragment …