[HTML][HTML] Extracellular vesicles engineering by silicates-activated endothelial progenitor cells for myocardial infarction treatment in male mice
B Yu, H Li, Z Zhang, P Chen, L Wang, X Fan… - Nature …, 2023 - nature.com
Extracellular vesicles have shown good potential in disease treatments including ischemic
injury such as myocardial infarction. However, the efficient production of highly active …
injury such as myocardial infarction. However, the efficient production of highly active …
[HTML][HTML] Cellular senescence affects cardiac regeneration and repair in ischemic heart disease
C Yan, Z Xu, W Huang - Aging and disease, 2021 - ncbi.nlm.nih.gov
Ischemic heart disease (IHD) is defined as a syndrome of ischemic cardiomyopathy.
Myogenesis and angiogenesis in the ischemic myocardium are important for cardiomyocyte …
Myogenesis and angiogenesis in the ischemic myocardium are important for cardiomyocyte …
Transplantation of endothelial progenitor cells: Summary and prospect
F Yan, J Li, W Zhang - Acta Histochemica, 2023 - Elsevier
Abstract Endothelial Progenitor Cells (EPCs) are precursor cells of endothelial cells (ECs),
which can differentiate into vascular ECs, protect from endothelial dysfunction and tissue …
which can differentiate into vascular ECs, protect from endothelial dysfunction and tissue …
[HTML][HTML] Regulation of endothelial progenitor cell functions in ischemic heart disease: new therapeutic targets for cardiac remodeling and repair
H Huang, W Huang - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Ischemic heart disease (IHD) is the leading cause of morbidity and mortality worldwide.
Ischemia and hypoxia following myocardial infarction (MI) cause subsequent cardiomyocyte …
Ischemia and hypoxia following myocardial infarction (MI) cause subsequent cardiomyocyte …
[HTML][HTML] Nicotinamide riboside enhances endothelial precursor cell function to promote refractory wound healing through mediating the Sirt1/AMPK pathway
Z Wang, X Bao, J Hu, S Shen, G Xu… - Frontiers in Pharmacology, 2021 - frontiersin.org
Lack of vascularization is directly associated with refractory wound healing in diabetes
mellitus (DM). Enrichment of endothelial precursor cells (EPCs) is a promising but …
mellitus (DM). Enrichment of endothelial precursor cells (EPCs) is a promising but …
[HTML][HTML] Latest advances in endothelial progenitor cell-derived extracellular vesicles translation to the clinic
AA Salybekov, AD Kunikeyev, S Kobayashi… - Frontiers in …, 2021 - frontiersin.org
Almost all nucleated cells secrete extracellular vesicles (EVs) that are heterogeneous
spheroid patterned or round shape particles ranging from 30 to 200 nm in size. Recent …
spheroid patterned or round shape particles ranging from 30 to 200 nm in size. Recent …
[HTML][HTML] The state of art of regenerative therapy in cardiovascular ischemic disease: biology, signaling pathways, and epigenetics of endothelial progenitor cells
Ischemic heart disease is currently a major cause of mortality and morbidity worldwide.
Nevertheless, the actual therapeutic scenario does not target myocardial cell regeneration …
Nevertheless, the actual therapeutic scenario does not target myocardial cell regeneration …
[HTML][HTML] New insights into the reparative angiogenesis after myocardial infarction
M Martín-Bórnez, D Falcón, R Morrugares… - International Journal of …, 2023 - mdpi.com
Myocardial infarction (MI) causes massive loss of cardiac myocytes and injury to the
coronary microcirculation, overwhelming the limited capacity of cardiac regeneration …
coronary microcirculation, overwhelming the limited capacity of cardiac regeneration …
[HTML][HTML] MiR-92a regulates endothelial progenitor cells (EPCs) by targeting GDF11 via activate SMAD2/3/FAK/Akt/eNOS pathway
HT Huang, ZC Liu, KQ Wu, SR Gu, TC Lu… - Annals of …, 2019 - ncbi.nlm.nih.gov
Background The effects of miR-92a on EPCs are still poorly elucidated. This study aimed to
investigate the effects of miR-92a on EPCs (Endothelial progenitor cells) in a model of …
investigate the effects of miR-92a on EPCs (Endothelial progenitor cells) in a model of …
[HTML][HTML] Computational analysis of serum-derived extracellular vesicle miRNAs in juvenile sheep model of single stage Fontan procedure
Patients with single ventricle heart defects requires a series of staged open-heart
procedures, termed Fontan palliation. However, while lifesaving, these operations are …
procedures, termed Fontan palliation. However, while lifesaving, these operations are …