Extracellular vesicles have shown good potential in disease treatments including ischemic
injury such as myocardial infarction. However, the efficient production of highly active …

Ischemic heart disease (IHD) is defined as a syndrome of ischemic cardiomyopathy.
Myogenesis and angiogenesis in the ischemic myocardium are important for cardiomyocyte …

Abstract Endothelial Progenitor Cells (EPCs) are precursor cells of endothelial cells (ECs),
which can differentiate into vascular ECs, protect from endothelial dysfunction and tissue …

Ischemic heart disease (IHD) is the leading cause of morbidity and mortality worldwide.
Ischemia and hypoxia following myocardial infarction (MI) cause subsequent cardiomyocyte …

Lack of vascularization is directly associated with refractory wound healing in diabetes
mellitus (DM). Enrichment of endothelial precursor cells (EPCs) is a promising but …

Almost all nucleated cells secrete extracellular vesicles (EVs) that are heterogeneous
spheroid patterned or round shape particles ranging from 30 to 200 nm in size. Recent …

Ischemic heart disease is currently a major cause of mortality and morbidity worldwide.
Nevertheless, the actual therapeutic scenario does not target myocardial cell regeneration …

Myocardial infarction (MI) causes massive loss of cardiac myocytes and injury to the
coronary microcirculation, overwhelming the limited capacity of cardiac regeneration …

Background The effects of miR-92a on EPCs are still poorly elucidated. This study aimed to
investigate the effects of miR-92a on EPCs (Endothelial progenitor cells) in a model of …

Patients with single ventricle heart defects requires a series of staged open-heart
procedures, termed Fontan palliation. However, while lifesaving, these operations are …