Removal of perineuronal nets in the medial prefrontal cortex impairs the acquisition and reconsolidation of a cocaine-induced conditioned place preference memory
M Slaker, L Churchill, RP Todd… - Journal of …, 2015 - Soc Neuroscience
Pyramidal neurons in the medial prefrontal cortex (mPFC) critically contribute to cocaine-
seeking behavior in humans and rodents. Activity of these neurons is significantly modulated …
seeking behavior in humans and rodents. Activity of these neurons is significantly modulated …
Phosphodiesterase 4 inhibitors and drugs of abuse: current knowledge and therapeutic opportunities
CM Olsen, QS Liu - Frontiers in biology, 2016 - Springer
Background Long-term exposure to drugs of abuse causes an upregulation of the cAMP-
signaling pathway in the nucleus accumbens and other forebrain regions, this common …
signaling pathway in the nucleus accumbens and other forebrain regions, this common …
The strength of aversive and appetitive associations and maladaptive behaviors
Y Itzhak, D Perez‐Lanza, S Liddie - IUBMB life, 2014 - Wiley Online Library
Certain maladaptive behaviors are thought to be acquired through classical Pavlovian
conditioning. Exaggerated fear response, which can develop through Pavlovian …
conditioning. Exaggerated fear response, which can develop through Pavlovian …
Sodium butyrate-induced histone acetylation strengthens the expression of cocaine-associated contextual memory
Y Itzhak, S Liddie, KL Anderson - Neurobiology of learning and memory, 2013 - Elsevier
The conditioned place preference (CPP) paradigm entails Pavlovian conditioning and
allows evaluating the acquisition and extinction of drug-associated memory. Epigenetic …
allows evaluating the acquisition and extinction of drug-associated memory. Epigenetic …
Cocaine conditioning induces persisting changes in ventral hippocampus synaptic transmission, long-term potentiation, and radial arm maze performance in the …
The effects of drugs of abuse, such as cocaine, on learning and memory processes are
thought to contribute to drug craving and relapse susceptibility. Using an Escalating (Esc) or …
thought to contribute to drug craving and relapse susceptibility. Using an Escalating (Esc) or …
The effect of phosphodiesterase inhibitors on the extinction of cocaine-induced conditioned place preference in mice
S Liddie, KL Anderson, A Paz… - Journal of …, 2012 - journals.sagepub.com
Several phosphodiesterase inhibitors (PDEis) improve cognition, suggesting that an
increase in brain cAMP and cGMP facilitates learning and memory. Since extinction of drug …
increase in brain cAMP and cGMP facilitates learning and memory. Since extinction of drug …
[HTML][HTML] Co-stimulation of muscarinic M1 and M4 acetylcholine receptors prevents later cocaine reinforcement in male and female mice, but not place-conditioning
AS Balakrishnan, LBE Johansen, CW Lindsley… - Progress in Neuro …, 2024 - Elsevier
Acute stimulation of M 1 or M 4 muscarinic cholinergic receptors reduces cocaine abuse-
related effects in mice and rats. The combined activation of these receptor subtypes …
related effects in mice and rats. The combined activation of these receptor subtypes …
A role for p38 mitogen-activated protein kinase-mediated threonine 30-dependent norepinephrine transporter regulation in cocaine sensitization and conditioned …
P Mannangatti, K NarasimhaNaidu, MI Damaj… - Journal of Biological …, 2015 - ASBMB
The noradrenergic and p38 mitogen-activated protein kinase (p38 MAPK) systems are
implicated in cocaine-elicited behaviors. Previously, we demonstrated a role for p38 MAPK …
implicated in cocaine-elicited behaviors. Previously, we demonstrated a role for p38 MAPK …
Neural correlates of cocaine-induced conditioned place preference in the posterior cerebellar cortex
O Rodríguez-Borillo, L Roselló-Jiménez… - Frontiers in Behavioral …, 2023 - frontiersin.org
Introduction Addictive drugs are potent neuropharmacological agents capable of inducing
long-lasting changes in learning and memory neurocircuitry. With repeated use, contexts …
long-lasting changes in learning and memory neurocircuitry. With repeated use, contexts …
NMDA antagonist MK 801 in nucleus accumbens core but not shell disrupts the restraint stress-induced reinstatement of extinguished cocaine-conditioned place …
LN De Giovanni, AS Guzman, MB Virgolini… - Behavioural Brain …, 2016 - Elsevier
Relapse is a common feature of cocaine addiction. In rodents, it can be elicited by cues,
stress or the drug. Restraint stress-induced reinstatement of cocaine-conditioned place …
stress or the drug. Restraint stress-induced reinstatement of cocaine-conditioned place …