Background CagA+ and vacuolizing cytotoxin (VacA)-specific strains of Helicobacter pylori
have been associated with different risks for developing gastric lesions. We aim to …

In the populations of Western countries, particular genotypes of the vacuolating cytotoxin
gene, vacA (vacA s, signal region variants; vacA m, middle region variants) of Helicobacter …

Helicobacter pylori is a Gram-negative, microaerophilic bacterium that colonizes the gastric
mucus overlying the epithelium of the stomach in more than 50% of the world's population …

Background Helicobacter pylori chronic infection is associated with chronic gastritis, peptic
ulcer, and gastric cancer. Cytotoxin-associated gene A (cagA)-positive H. pylori strains …

The cytotoxin-associated gene A (cagA), and the vacuolating cytotoxin gene A (vacA)
products are considered the most important pathogenic determinants of Helicobacter pylori …

Abstract Background Outcome of Helicobacter pylori (H. pylori) infection results from
interaction of multiple variables including host, environmental and bacterial-associated …

The aim of this study was to investigate genetic diversity of Helicobacter pylori virulence
markers to predict clinical outcome as well as to determine an antibiotic susceptibility of H …

Epidemiological studies have reported the relationship between vacuolating cytotoxin A
(vacA) s-/m-region genotypes and duodenal ulcer (DU), but the results remained …

Infection by Helicobacter pylori is associated with the development of several
gastroduodenal diseases, including gastritis, peptic ulcer disease (gastric ulcers and …

Background At present, the relationship between virulence factors of Helicobacter pylori (H.
pylori) and gastrointestinal diseases is still under discussion. This study investigated the …