Endocrine‐disrupting chemicals (EDC s) are man‐made chemicals that interfere with
hormonal signalling pathways. They are used in, for example, production of common …

The process of DNA CpG methylation has been extensively investigated for over 50 years
and revealed associations between changing methylation status of CpG islands and gene …

Oxidative stress occurs when cellular reactive oxygen species levels exceed the self-
antioxidant capacity of the body. Oxidative stress induces many pathological changes …

Prostate cancer (PCa) is the second most common diagnosed malignant disease in men
worldwide. Although serum PSA test dramatically improved the early diagnosis of PCa, it …

Fetal alcohol spectrum disorders (FASD) are a group of related conditions that arise from
prenatal exposure to maternal consumption of the teratogen, ethanol. It has been estimated …

Studies have shown that miR-221 and miR-222 are deregulated in many cancers, including
prostate cancer. Nevertheless, the biological role and the underlying mechanisms of miR …

miRNAs are short noncoding RNAs able to regulate specific mRNA stability, thus influencing
target gene expression. Disrupted levels of several miRNAs have been associated with …

Background: The role of global DNA methylation in prostate cancer (PCa) remains largely
unknown. Our aim was to summarize evidence on the role of global DNA hypomethylation in …

Background: Usually, chemoradiotherapy can be used for the treatment of locally advanced
colorectal cancer (CRC) before surgery. On the other hand, some studies have shown that …

Nuclear receptors (NR) act as an integrated conduit for environmental and hormonal signals
to govern genomic responses, which relate to cell fate decisions. We review how their …