In multicellular organisms, homeostasis is maintained through a balance between cell
proliferation and cell death. Although much is known about the control of cell proliferation …

It is well established that axonal regeneration in the adult CNS is largely unsuccessful.
Numerous axon‐inhibitory molecules are now known to be present in the injured CNS, and …

Perineuronal nets (PNs) are known as chondroitin sulphate-rich, lattice-like coatings of the
extracellular matrix. In the cortex of mammalian species investigated so far, they were mainly …

Brain tumor patients commonly present with epileptic seizures. We show that tumor-
associated seizures are the consequence of impaired GABAergic inhibition due to an overall …

The extracellular matrix (ECM) of the central nervous system (CNS) occupies a large part of
the neural tissue. It serves a variety of functions ranging from support of cell migration and …

Perineuronal nets (PNNs) are condensed extracellular matrix (ECM) assemblies of
polyanionic chondroitin sulfate proteoglycans, hyaluronan, and tenascins that primarily wrap …

Perineuronal nets (PNs) are a specialized form of brain extracellular matrix, consisting of
negatively charged glycosaminoglycans, glycoproteins and proteoglycans in the direct …

Perineuronal nets (PNs) are a specialized form of extracellular matrix, surrounding different
types of neurons and mainly consist of chondroitin sulfate proteoglycans connected to …

Brain extracellular matrix (ECM) structure mediates many aspects of neural development
and function. Probing structural changes in brain ECM could thus provide insights into …

Proteoglycans (PGs) are complex macromolecules of the extracellular matrix (ECM) that
have a wide variety of effects on developing and regenerating neurons in vivo and in vitro …