Osteoarthritis: New insight on its pathophysiology

S Coaccioli, P Sarzi-Puttini, P Zis, G Rinonapoli… - Journal of Clinical …, 2022 - mdpi.com
Understanding of the basis of osteoarthritis (OA) has seen some interesting advancements
in recent years. It has been observed that cartilage degeneration is preceded by …

Knee osteoarthritis: Current status and research progress in treatment

R Geng, J Li, C Yu, C Zhang… - Experimental and …, 2023 - spandidos-publications.com
Knee osteoarthritis (KOA) is a common chronic articular disease worldwide. It is also the
most common form of OA and is characterized by high morbidity and disability rates. With the …

How to study anxiety and depression in rodent models of chronic pain?

M Kremer, LJ Becker, M Barrot… - European Journal of …, 2021 - Wiley Online Library
Mood disorders such as depression and anxiety are frequently observed in patients
suffering from chronic pain. Over time, different tests and models have been developed in …

Osteoarthritis-related knee pain treated with genicular artery embolization: a systematic review and meta-analysis

P Torkian, J Golzarian, M Chalian… - … Journal of Sports …, 2021 - journals.sagepub.com
Background: Genicular artery embolization (GAE) is an innovative technique that has been
investigated as a supplementary treatment method for chronic pain secondary to knee …

Low-grade inflammation in the pathogenesis of osteoarthritis: Cellular and molecular mechanisms and strategies for future therapeutic intervention

MA Terkawi, T Ebata, S Yokota, D Takahashi, T Endo… - Biomedicines, 2022 - mdpi.com
Osteoarthritis (OA) is a musculoskeletal disease characterized by cartilage degeneration
and stiffness, with chronic pain in the affected joint. It has been proposed that OA …

Obesity, Metabolic Syndrome, and Osteoarthritis—An Updated Review

SJP Sampath, V Venkatesan, S Ghosh… - Current Obesity …, 2023 - Springer
Abstract Purpose of Review Metabolic syndrome (MetS), also called the 'deadly
quartet'comprising obesity, diabetes, dyslipidemia, and hypertension, has been ascertained …

[HTML][HTML] OA foundations–experimental models of osteoarthritis

S Zaki, CL Blaker, CB Little - Osteoarthritis and Cartilage, 2022 - Elsevier
Osteoarthritis (OA) is increasingly recognised as a disease of diverse phenotypes with
variable clinical presentation, progression, and response to therapeutic intervention. This …

The impact of pain on quality of life in patients with osteoarthritis: a cross-sectional study from Palestine

M Shalhoub, M Anaya, S Deek, AH Zaben… - BMC musculoskeletal …, 2022 - Springer
Background Osteoarthritis is one of the most common musculoskeletal problems. Pain is the
most common complaint and the most significant cause of decreased health-related quality …

Burden of knee osteoarthritis in the Middle East and North Africa (MENA): an epidemiological analysis from 1990 to 2019

AH Hoveidaei, A Nakhostin-Ansari, M Chalian… - Archives of Orthopaedic …, 2023 - Springer
Background Knee is the most affected joint in osteoarthritis (OA) and accounts for almost
four-fifths of the burden of OA globally. We aimed to explore the prevalence, incidence …

Prevalence of symptomatic knee osteoarthritis in Saudi Arabia and associated modifiable and non-modifiable risk factors: a population-based cross-sectional study

OW Althomali, J Amin, T Acar, S Shahanawaz… - Healthcare, 2023 - mdpi.com
Objective: This study aimed to determine the prevalence of knee osteoarthritis (OA) in Saudi
Arabia and the association between knee OA and modifiable and non-modifiable risk …