Currently, skin injuries have a serious impact on people's lives and socio-economic stress.
Shikonin, a naphthoquinone compound derived from the root of the traditional Chinese …

The liver plays a vital role in metabolism, synthesis, and detoxification, but it is susceptible to
damage from various factors such as viral infections, drug reactions, excessive alcohol …

Triple-negative breast cancer (TNBC) is an aggressive phenotype that lacks effective
therapies. Amplification of oxidative stress is reportedly effective against tumors. Shikonin …

Drug-induced liver injury (DILI) remains one of the major concerns for healthcare providers
and patients. Unfortunately, it is difficult to predict and prevent DILI in the clinic because …

In recent years, foodborne pollutants have become a hot issue in the field of food safety. 3‐
chloro‐1, 2‐propanediol (3‐MCPD) is a widely existing food contaminant. In our previous …

Background Adverse effects of benzene (BZ) exposure toxicities were documented by many
researchers worldwide. BZ exposure causes many hematological abnormalities that might …

Introduction Non-steroidal anti-inflammatory drugs and opioids are widely prescribed for the
treatment of mild to severe pain. Wide interindividual variability regarding the analgesic …

Molecules | Free Full-Text | Correction: Li et al. Shikonin Attenuates Acetaminophen-Induced
Hepatotoxicity by Upregulation of Nrf2 through Akt/GSK3β Signaling. Molecules 2019, 24 …

We investigated the effect of GSK-3β RNAi lentivirus on neuronal damage and Nrf2 level in
rats with cerebral infarction. 40 rats were assigned into sham group, CI group, Vector group …

Shikonin (β-alkannin) is one of the main active components isolated from the Chinese herb
Lithospermum Erythrorhizon. Shikonin shows pleiotropic medical properties, such as …