[HTML][HTML] Clinically relevant therapeutic approaches against acetaminophen hepatotoxicity and acute liver failure
Liver injury and acute liver failure caused by an acetaminophen (APAP) overdose is a
significant clinical problem in western countries. With the introduction of the mouse model of …
significant clinical problem in western countries. With the introduction of the mouse model of …
Ethanol Extract of Rosa rugosa Ameliorates Acetaminophen-Induced Liver Injury via Upregulating Sirt1 and Subsequent Potentiation of LKB1/AMPK/Nrf2 Cascade in …
Y Lei, X Lei, A Zhu, S Xie, T Zhang, C Wang, A Song… - Molecules, 2023 - mdpi.com
Acetaminophen (APAP)-induced liver injury is a common hepatic disease resulting from
drug abuse. Few targeted treatments are available clinically nowadays. The flower bud of …
drug abuse. Few targeted treatments are available clinically nowadays. The flower bud of …
Cynarin alleviates acetaminophen-induced acute liver injury through the activation of Keap1/Nrf2-mediated lipid peroxidation defense via the AMPK/SIRT3 signaling …
L Zhao, X Zhang, Z Chen, Y Lai, J Xu, R Zhou, P Ma… - Food & Function, 2024 - pubs.rsc.org
Overdose of Acetaminophen (APAP) is a major contributor to acute liver injury (ALI), a
complex pathological process with limited effective treatments. Emerging evidence links lipid …
complex pathological process with limited effective treatments. Emerging evidence links lipid …
Direct targeting of S100A9 with Icariin counteracted acetaminophen‑induced hepatotoxicity
P Shen, M Xue, Z Hu, L Han, X Deng - International Immunopharmacology, 2024 - Elsevier
Acetaminophen (APAP) is a widely used antipyretic and analgesic medication, but its
overdose can induce acute liver failure with lack of effective therapies. Icariin is a bioactive …
overdose can induce acute liver failure with lack of effective therapies. Icariin is a bioactive …
Effect of ferroptosis inhibitors in a murine model of acetaminophen‐induced liver injury
Liver injury caused by acetaminophen (APAP) overdose is the leading cause of acute liver
failure in western countries. The mode of APAP‐induced cell death has been controversially …
failure in western countries. The mode of APAP‐induced cell death has been controversially …
[HTML][HTML] The role of alpha lipoic acid and tempol against liver injury after acetaminophen subacute exposure in mice
FM Al-Rekabi, SM Alrobyrai - Adv. Anim. Vet. Sci, 2024 - researcherslinks.com
Acetaminophen (APAP) is a widely used analgesic and antipyretic drug, but it can cause
liver damage when taken in high doses or for prolonged periods. Alpha Lipoic Acid (ALA) …
liver damage when taken in high doses or for prolonged periods. Alpha Lipoic Acid (ALA) …
[引用][C] Comments on: Unveiling the therapeutic promise of natural products in alleviating drug‐induced liver injury: Present advancements and future prospects
H Jaeschke, A Ramachandran - Phytotherapy Research, 2024 - Wiley Online Library