Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy

Q Lu, D Kou, S Lou, M Ashrafizadeh, AR Aref… - Journal of Hematology & …, 2024 - Springer
Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …

Ultrathin Clay Nanoparticles‐Mediated Mutual Reinforcement of Ferroptosis and Cancer Immunotherapy

J Liu, J Zhan, Y Zhang, L Huang, J Yang… - Advanced …, 2024 - Wiley Online Library
Ferroptosis‐triggered immunogenic cell death (ICD) is widely adopted to potentiate the
body's antitumor immunity by catalyzing the production of toxic reactive oxygen species …

CaCO 3 nanoplatform for cancer treatment: drug delivery and combination therapy

X Yang, Y Sun, H Zhang, F Liu, Q Chen, Q Shen… - Nanoscale, 2024 - pubs.rsc.org
The use of nanocarriers for drug delivery has opened up exciting new possibilities in cancer
treatment. Among them, calcium carbonate (CaCO3) nanocarriers have emerged as a …

Nano-modulators with the function of disrupting mitochondrial Ca2+ homeostasis and photothermal conversion for synergistic breast cancer therapy

C Wang, T Li, Z Wang, Y Li, Y Liu, M Xu… - Journal of …, 2023 - Springer
Breast cancer treatment has been a global puzzle, and apoptosis strategies based on
mitochondrial Ca2+ overload have attracted extensive attention. However, various …

Biomimetic MOF‐Based Nano‐Immunoactivator via Disruption of Ion Homeostasis for Strengthened Tumor Microwave‐Immunotherapy

Z Chen, W Guo, L Tan, C Fu, Q Wu… - Advanced Functional …, 2024 - Wiley Online Library
Immunogenic cell death (ICD) is a promising strategy for anticancer immunity by inducing
antigen‐presenting cell maturation. However, the traditional ICD inducers, such as …

Cancer diagnosis and treatment platform based on manganese-based nanomaterials

J Fei, Y Liu, Y Zeng, M Yang, S Chen… - … in Bioengineering and …, 2024 - frontiersin.org
Cancer is a leading cause of death worldwide, and the development of new diagnostic and
treatment methods is crucial. Manganese-based nanomaterials (MnNMs) have emerged as …

A multifunctional fluorescent probe for tracking SO2 fluctuation between mitochondria and endoplasmic reticulum in living cells and zebrafish

H Zhang, F Li, Q Li, C Liang, Y Wei, C Zhou… - Sensors and Actuators B …, 2024 - Elsevier
Abstract The sulfur dioxide (SO 2)-associated dynamic interplay between mitochondria
(Mito) and endoplasmic reticulum (ER) is essential for intracellular homeostasis regulation …

Free Radicals Generated in Perfluorocarbon–Water (Liquid–Liquid) Interfacial Contact Electrification and Their Application in Cancer Therapy

H Li, Z Wang, X Chu, Y Zhao, G He, Y Hu… - Journal of the …, 2024 - ACS Publications
Electron transfer during solid–liquid contact electrification has been demonstrated to
produce reactive oxygen species (ROS) such as hydroxyl radicals (• OH) and superoxide …

Intelligent Biogenic Missile for Two-Photon Fluorescence Imaging-Guided Combined Photodynamic Therapy and Chemotherapy in Tumors

Z Qian, K He, R Feng, J Chen, B Li, Y Zhang… - Analytical …, 2024 - ACS Publications
Photodynamic therapy (PDT) is a significant noninvasive therapeutic modality, but it is often
limited in its application due to the restricted tissue penetration depth caused by the …

Outer membrane vesicle-wrapped manganese nanoreactor for augmenting cancer metalloimmunotherapy through hypoxia attenuation and immune stimulation

S Luo, Y Yang, L Chen, PR Kannan, W Yang, Y Zhang… - Acta Biomaterialia, 2024 - Elsevier
Tumor hypoxia, high oxidative stress, and low immunogenic create a deep-rooted
immunosuppressive microenvironment, posing a major challenge to the therapeutic …