Animal models of Alzheimer disease: historical pitfalls and a path forward
SE Cavanaugh, JJ Pippin, ND Barnard - ALTEX-Alternatives to animal …, 2014 - altex.org
Alzheimer disease (AD) is a medically and financially overwhelming condition, and
incidence rates are expected to triple by 2050. Despite decades of research in animal …
incidence rates are expected to triple by 2050. Despite decades of research in animal …
Moderate-to-high intensity physical exercise in patients with Alzheimer's disease: a randomized controlled trial
K Hoffmann, NA Sobol, KS Frederiksen… - Journal of …, 2016 - content.iospress.com
Background: Studies of physical exercise in patients with Alzheimer's disease (AD) are few
and results have been inconsistent. Objective: To assess the effects of a moderate-to-high …
and results have been inconsistent. Objective: To assess the effects of a moderate-to-high …
The impact of obesity and exercise on cognitive aging
JSY Chan, JH Yan, VG Payne - Frontiers in aging neuroscience, 2013 - frontiersin.org
Obesity is a major concern in the aging population and degrades health, motor functions
and cognition in older adults. The effects of obesity are pervasive and challenging to health …
and cognition in older adults. The effects of obesity are pervasive and challenging to health …
Exploring the bidirectional associations between loneliness and cognitive functioning over 10 years: the English longitudinal study of ageing
Background As the population ages, cognitive decline and dementia have become major
health concerns in the UK. Loneliness has been linked to cognitive decline, but the reverse …
health concerns in the UK. Loneliness has been linked to cognitive decline, but the reverse …
Moderate-intensity physical activity, hippocampal volume, and memory in older adults with mild cognitive impairment
H Makizako, T Liu-Ambrose, H Shimada… - … Series A: Biomedical …, 2015 - academic.oup.com
Background. Greater physical activity (PA) is associated with better memory performance
and greater hippocampal volume in older adults. However, most studies to date assessed …
and greater hippocampal volume in older adults. However, most studies to date assessed …
Life experience and demographic influences on cognitive function in older adults.
Objective: We examined the influence of a broad spectrum of life experiences on
longitudinal cognitive trajectories in a demographically diverse sample of older adults …
longitudinal cognitive trajectories in a demographically diverse sample of older adults …
Physical activity is positively associated with episodic memory in aging
Aging is associated with performance reductions in executive function and episodic memory,
although there is substantial individual variability in cognition among older adults. One factor …
although there is substantial individual variability in cognition among older adults. One factor …
The role of physical and cognitive function in performance of activities of daily living in patients with mild-to-moderate Alzheimer's disease–a cross-sectional study
FK Clemmensen, K Hoffmann, V Siersma, N Sobol… - BMC geriatrics, 2020 - Springer
Background Several factors may play a role in the ability of patients with Alzheimer's disease
to perform activities of daily living (ADL). The aim of this study was to examine the impact of …
to perform activities of daily living (ADL). The aim of this study was to examine the impact of …
[HTML][HTML] Patients with Alzheimer's disease who carry the APOE ε4 allele benefit more from physical exercise
CS Jensen, AH Simonsen, V Siersma, N Beyer… - Alzheimer's & Dementia …, 2019 - Elsevier
Introduction Our group has completed an exercise study of 200 patients with mild
Alzheimer's disease. We found improvements in cognitive, neuropsychiatric, and physical …
Alzheimer's disease. We found improvements in cognitive, neuropsychiatric, and physical …
Light physical activity is positively associated with cognitive performance in older community dwelling adults
Objectives To evaluate the associations between an objective measure of different
intensities of physical activity, upper-and lower-limb muscle strength and psychomotor …
intensities of physical activity, upper-and lower-limb muscle strength and psychomotor …