Lymphatic pumping: mechanics, mechanisms and malfunction

JP Scallan, SD Zawieja… - The Journal of …, 2016 - Wiley Online Library
A combination of extrinsic (passive) and intrinsic (active) forces move lymph against a
hydrostatic pressure gradient in most regions of the body. The effectiveness of the lymph …

Intestinal lymphatic vasculature: structure, mechanisms and functions

J Bernier-Latmani, TV Petrova - Nature reviews Gastroenterology & …, 2017 - nature.com
The mammalian intestine is richly supplied with lymphatic vasculature, which has functions
ranging from maintenance of interstitial fluid balance to transport of antigens, antigen …

Photobiomodulation therapy and the glymphatic system: promising applications for augmenting the brain lymphatic drainage system

F Salehpour, M Khademi, DE Bragin… - International journal of …, 2022 - mdpi.com
The glymphatic system is a glial-dependent waste clearance pathway in the central nervous
system, devoted to drain away waste metabolic products and soluble proteins such as …

The diagnostic approach and current management of chylous ascites

B Lizaola, A Bonder, HD Trivedi… - Alimentary …, 2017 - Wiley Online Library
Background Chylous ascites is rare, accounting for less than 1% of cases. An appropriate
and stepwise approach to its diagnosis and management is of key importance. Aim To …

Pilot study of transcranial photobiomodulation of lymphatic clearance of beta-amyloid from the mouse brain: breakthrough strategies for non-pharmacologic therapy of …

E Zinchenko, N Navolokin, A Shirokov… - Biomedical optics …, 2019 - opg.optica.org
In this pilot study, we analyzed effects of transcranial photobiomodulation (tPBM, 1267 nm,
32 J/cm^ 2) on clearance of beta-amyloid (Aβ) from the mouse brain. The …

Flow-induced stress on adherent cells in microfluidic devices

J Shemesh, I Jalilian, A Shi, GH Yeoh, MLK Tate… - Lab on a Chip, 2015 - pubs.rsc.org
Transduction of mechanical forces and chemical signals affect every cell in the human body.
Fluid flow in systems such as the lymphatic or circulatory systems modulates not only cell …

Targeting lymphatic function as a novel therapeutic intervention for rheumatoid arthritis

EM Bouta, RD Bell, H Rahimi, L Xing… - Nature Reviews …, 2018 - nature.com
Although clinical outcomes for patients with rheumatoid arthritis (RA) have greatly improved
with the use of biologic and conventional DMARDs, approximately 40% of patients do not …

Hydrodynamics in cell studies

D Huber, A Oskooei, X Casadevall i Solvas… - Chemical …, 2018 - ACS Publications
Hydrodynamic phenomena are ubiquitous in living organisms and can be used to
manipulate cells or emulate physiological microenvironments experienced in vivo …

Development and physiological functions of the lymphatic system: insights from human genetic studies of primary lymphedema

S Martin-Almedina, PS Mortimer… - Physiological …, 2021 - journals.physiology.org
Primary lymphedema is a long-term (chronic) condition characterized by tissue lymph
retention and swelling that can affect any part of the body, although it usually develops in the …

KATP channels in lymphatic function

MJ Davis, HJ Kim, CG Nichols - American Journal of …, 2022 - journals.physiology.org
KATP channels function as negative regulators of active lymphatic pumping and lymph
transport. This review summarizes and critiques the evidence for the expression of specific …